TheraRadar
← Back
Data updated: Jun 28, 2026

AGIOS PHARMS INC

Pharma
Pharmaceuticals Execution: Fair

AGIOS PHARMS INC is a pharmaceutical company with 2 FDA-approved products.

2022
Since
2
Drugs
-
Trials
0
New Drugs (2yr)
Modality:
2 Small Molecules

FDA Novel Drug Designations

(2022)
1 Novel 1 First-in-Class 1 Orphan 1 Priority Review 1 Fast Track
See 1 novel approval →
2022 PYRUKYND (MITAPIVAT SULFATE) First-in-Class · Orphan · Priority Review · Fast Track

AGIOS PHARMS INC at a Glance

  • Fast trial execution (5 months median completion)

AGIOS PHARMS INC's Key Drugs

AGIOS PHARMS INC's core commercial portfolio centers on PYRUKYND, AQVESME — its most strategically important drugs approved in the last 15 years.

AGIOS PHARMS INC's Recent FDA Approvals

New NDA/BLA approvals for AGIOS PHARMS INC over the last two years — novel drugs only, excluding generics and label supplements.

No recent approvals

AGIOS PHARMS INC's Therapeutic Areas

Disease areas where AGIOS PHARMS INC has approved drugs and an active pipeline. Weighted by commercial stage — approved drugs count most, then late-stage trials.

No indication data

AGIOS PHARMS INC Pipeline Snapshot

Active clinical trials for AGIOS PHARMS INC across all therapeutic areas, from ClinicalTrials.gov.

No active pipeline data available

Phase 3 Readout Calendar Pro

3 Phase 3 trials with confidence-graded primary completion dates.

Full calendar →
Q1 2029
Mitapivat
Non-Transfusion-dependent Alpha-Thalassemia
Estimated · fresh NCT07517133
Q2 2029
Mitapivat Matched Placebo
Transfusion-dependent Alpha-Thalassemia
Estimated · fresh NCT07506863
Q4 2025
Mitapivat
Sickle Cell Disease
Completed · awaiting NCT05031780

Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Pro Intelligence Preview

Deep insights for investors and analysts

Revenue Insights

  • PYRUKYND leads revenue
  • 2 key drugs tracked
View revenue breakdown →

Trial Catalysts

  • Active trial monitoring
  • 3 Phase 3 readouts tracked
View readout calendar →

Patent Risk

  • Patent expiration timeline
  • Revenue at risk analysis
View patent timeline →

Compare Companies

  • Side-by-side pipeline analysis
  • Revenue & market share comparison
Compare with competitor →

Execution Intelligence

  • Phase 3: 3/9 completed
  • Speed: 5 months avg
Unlock Full Intelligence

Revenue forecasts • Trial milestones • Patent risk modeling

How We Calculate These Metrics

Execution Quality Score

Measures trial completion rates weighted by phase importance. Phase 3 trials count 4x more than Phase 1 because late-stage completion is harder and more valuable.

What counts as "completed": A trial that reached its planned endpoint and reported results. Trials that were terminated early, withdrawn, or suspended are not counted as completed—these often indicate safety issues, lack of efficacy, or strategic pivots.

  • Excellent (80%+): Top-tier execution, most trials reach planned endpoints
  • Good (60-79%): Strong execution with occasional early terminations
  • Fair (40-59%): Average execution, notable rate of terminated/withdrawn trials
  • Needs Improvement (under 40%): High termination rates, execution challenges