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Data updated: Jun 28, 2026

EXELIXIS

Specialty
OncologyMetabolicGastroenterology Execution: Needs Improvement

EXELIXIS is a specialty pharmaceutical company focused on Oncology, Metabolic, Gastroenterology. Key products include CABOMETYX.

2012
Since
2
Drugs
-
Trials
0
New Drugs (2yr)
Modality:
2 Small Molecules

EXELIXIS at a Glance

  • Growing R&D activity with 8 trials in last 2 years

Upcoming FDA Decisions

Full Calendar →
Dec 3, 2026 — Zanzalintinib (XL-092) + atezolizumab
Jan 20, 2027 — Foundayo (orforglipron)

EXELIXIS's Key Drugs

EXELIXIS's core commercial portfolio centers on CABOMETYX, COMETRIQ, spanning Oncology and Metabolic — its most strategically important drugs approved in the last 15 years.

EXELIXIS's Recent FDA Approvals

New NDA/BLA approvals for EXELIXIS over the last two years — novel drugs only, excluding generics and label supplements.

No recent approvals

EXELIXIS's Therapeutic Areas

EXELIXIS's approved drugs and pipeline span 3 therapeutic areas, led by Oncology and Metabolic, across 0 biologic and 2 small-molecule drugs. Weighted by commercial stage — approved drugs count most, then late-stage trials.

Oncology 75%
2 drugs Phase 3: 12 Phase 2: 5 Phase 1: 19
Metabolic 23%
2 drugs Phase 3: 3 Phase 1: 3
Gastroenterology 3%
0 drugs Phase 1: 3

EXELIXIS's Top Competitors

EXELIXIS's closest competitors by therapeutic-area and drug-target overlap include Johnson & Johnson, Takeda, and ASTELLAS. Ranked by overlap in therapeutic areas and drug targets across approved drugs and pipeline.

EXELIXIS Pipeline Snapshot

EXELIXIS has 45 active clinical programs from ClinicalTrials.gov — 15 Phase 3, 5 Phase 2 and 25 Phase 1.

15
Phase 3
5
Phase 2
25
Phase 1

Phase 3 Readout Calendar Pro

2 Phase 3 trials with confidence-graded primary completion dates.

Full calendar →
Q3 2028
Zanzalintinib
Head and Neck Squamous Cell Carcinoma
Estimated · aging NCT06082167
Q2 2029
Zanzalintinib
Pancreatic Neuroendocrine Tumor (pNET)
Estimated · fresh NCT06943755

Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Pro Intelligence Preview

Deep insights for investors and analysts

Revenue Insights

  • CABOMETYX leads revenue
  • 2 key drugs tracked
View revenue breakdown →

Trial Catalysts

  • Oncology pipeline focus
  • 2 Phase 3 readouts tracked
View readout calendar →

Patent Risk

  • Patent expiration timeline
  • Revenue at risk analysis
View patent timeline →

Compare Companies

  • Side-by-side pipeline analysis
  • Revenue & market share comparison
Compare with competitor →

Execution Intelligence

  • Phase 3: 4/11 completed
  • Speed: 41 months avg
Unlock Full Intelligence

Revenue forecasts • Trial milestones • Patent risk modeling

How We Calculate These Metrics

Execution Quality Score

Measures trial completion rates weighted by phase importance. Phase 3 trials count 4x more than Phase 1 because late-stage completion is harder and more valuable.

What counts as "completed": A trial that reached its planned endpoint and reported results. Trials that were terminated early, withdrawn, or suspended are not counted as completed—these often indicate safety issues, lack of efficacy, or strategic pivots.

  • Excellent (80%+): Top-tier execution, most trials reach planned endpoints
  • Good (60-79%): Strong execution with occasional early terminations
  • Fair (40-59%): Average execution, notable rate of terminated/withdrawn trials
  • Needs Improvement (under 40%): High termination rates, execution challenges