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Data updated: Jun 28, 2026

LEXICON PHARMS INC

Pharma
CardiovascularMetabolic Execution: Excellent

LEXICON PHARMS INC is a pharmaceutical company focused on Cardiovascular, Metabolic. Key products include INPEFA.

2023
Since
1
Drugs
-
Trials
0
New Drugs (2yr)
Modality:
1 Small Molecules

FDA Novel Drug Designations

(2023)
1 Novel
See 1 novel approval →
2023 INPEFA (SOTAGLIFLOZIN)

LEXICON PHARMS INC at a Glance

  • Strong track record with 86% execution quality across 60 trials
  • Fast trial execution (21 months median completion)

LEXICON PHARMS INC's Key Drugs

LEXICON PHARMS INC's core commercial portfolio centers on INPEFA, spanning Cardiovascular and Metabolic — its most strategically important drugs approved in the last 15 years.

LEXICON PHARMS INC's Recent FDA Approvals

New NDA/BLA approvals for LEXICON PHARMS INC over the last two years — novel drugs only, excluding generics and label supplements.

No recent approvals

LEXICON PHARMS INC's Therapeutic Areas

LEXICON PHARMS INC's approved drugs and pipeline span 2 therapeutic areas, led by Cardiovascular and Metabolic, across 0 biologic and 1 small-molecule drug. Weighted by commercial stage — approved drugs count most, then late-stage trials.

Cardiovascular 50%
1 drugs
Metabolic 50%
1 drugs

LEXICON PHARMS INC's Top Competitors

LEXICON PHARMS INC's closest competitors by therapeutic-area and drug-target overlap include Merck, Baxter, and Sanofi. Ranked by overlap in therapeutic areas and drug targets across approved drugs and pipeline.

LEXICON PHARMS INC Pipeline Snapshot

Active clinical trials for LEXICON PHARMS INC across all therapeutic areas, from ClinicalTrials.gov.

No active pipeline data available

Phase 3 Readout Calendar Pro

1 Phase 3 trial with confidence-graded primary completion dates.

Full calendar →
Q3 2026
Sotagliflozin
Obstructive Cardiomyopathy, Hypertrophic
Estimated · fresh NCT06481891

Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Pro Intelligence Preview

Deep insights for investors and analysts

Revenue Insights

  • INPEFA leads revenue
  • Drug-level revenue analysis

Trial Catalysts

  • Cardiovascular pipeline focus
  • 1 Phase 3 readout tracked
View readout calendar →

Patent Risk

  • Patent expiration timeline
  • Revenue at risk analysis

Compare Companies

  • Side-by-side pipeline analysis
  • Revenue & market share comparison

Execution Intelligence

  • Phase 3: 14/18 completed
  • Speed: 21 months avg
Unlock Full Intelligence

Revenue forecasts • Trial milestones • Patent risk modeling

How We Calculate These Metrics

Execution Quality Score

Measures trial completion rates weighted by phase importance. Phase 3 trials count 4x more than Phase 1 because late-stage completion is harder and more valuable.

What counts as "completed": A trial that reached its planned endpoint and reported results. Trials that were terminated early, withdrawn, or suspended are not counted as completed—these often indicate safety issues, lack of efficacy, or strategic pivots.

  • Excellent (80%+): Top-tier execution, most trials reach planned endpoints
  • Good (60-79%): Strong execution with occasional early terminations
  • Fair (40-59%): Average execution, notable rate of terminated/withdrawn trials
  • Needs Improvement (under 40%): High termination rates, execution challenges