TheraRadar
Landscape / Endocrine
Data updated: Jun 28, 2026

Adrenal Insufficiency Clinical Trial Landscape

Adrenal Insufficiency is being studied across 30 clinical trials registered since 2008, with 4 programs currently active. The competitive pipeline includes 0 active Phase 3 trials, 0 active Phase 2 trials, and 0 active Phase 1 trials.

Top industry sponsors include Neurocrine UK Limited.

Trial activity

4 active / 30 total since 2008
Active by phase 0 Ph3 / 6 0 Ph2 / 6 0 Ph1 / 6 4 Ph4 / 12

Sponsor activity

Who is running trials now — green active, blue completed, red failed/terminated.

Sorted by active Active Done Failed
Neurocrine UK Limited 0 10 0

How the field has grown

New-trial starts peaked in 2021 (4 registered); 2025 saw 1. The right-hand chart shows median Phase 3 enrollment by start year — the number in parentheses is that year's Phase 3 trial count (2 in total), so single-trial years (and years with no Phase 3 starts) are obvious. Both are by trial start date; the current year is partial.

New trials started by year

2016
1
2017
2
2018
3
2019
1
2020
0
2021
4
2022
2
2023
0
2024
1
2025
1
2026
0

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Median Phase 3 enrollment by start year

2016 (1)
18
2017 (0)
0
2018 (1)
100
2019 (0)
0
2020 (0)
0
2021 (0)
0
2022 (0)
0
2023 (0)
0
2024 (0)
0
2025 (0)
0
2026 (0)
0

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Full trial pipeline

Every active and completed trial across Phase 1–4, with enrollment analytics. Sortable, filterable, exportable with Pro.

NCT06260462 COMPLETED
Effects of Steroid Replacement Therapy on Metabolic, Cardiovascular and Bone Outcomes in Adrenal Insufficiency
University of Palermo n=88
NCT02720952 COMPLETED
Treatment of Adrenal Insufficiency in Children
Neurocrine UK Limited n=24
NCT03368066 COMPLETED
Is Adrenal Insufficiency Under-diagnosed in Hospitalized Cirrhosis Patients?
University of Virginia n=100
NCT02733367 COMPLETED
Extension Study for Patients Entered Into Study Infacort 003
Neurocrine UK Limited n=18
NCT01093261 COMPLETED
Corticosteroid Therapy for Glucocorticoid Insufficiency Related to Traumatic Brain Injury
Nantes University Hospital n=336
NCT01063569 COMPLETED
Glucocorticoid Treatment in Addison's Disease
Haukeland University Hospital n=33

Full Adrenal Insufficiency Pipeline

Every trial across Phase 1–4, plus enrollment analytics. Sortable, filterable, exportable.

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Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only