NCT06092333 RECRUITING VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT06829329 ACTIVE NOT RECRUITING Study to Evaluate the Efficacy and Safety of AHB-137 in Treatment-naive Participants With Chronic Hepatitis B (CHB)
Ausper Biopharma Co., Ltd.
NCT06550128 ACTIVE NOT RECRUITING Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB).
Ausper Biopharma Co., Ltd.
NCT06993480 ACTIVE NOT RECRUITING A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Ausper Biopharma Co., Ltd.
NCT07137910 RECRUITING A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Ausper Biopharma Co., Ltd.
NCT06963710 RECRUITING A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Aligos Therapeutics
NCT07417553 RECRUITING A Study of Hydronidone Capsules in Patients With Chronic Hepatitis B Virus-Related Liver Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.
NCT07370207 RECRUITING Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region
AusperBio Therapeutics Inc.
NCT07519330 RECRUITING Clinical Study to Evaluate the Efficacy and Safety of HH-006 in Patients With Chronic Hepatitis B Virus Infection
Huahui Health
NCT02932150 ACTIVE NOT RECRUITING Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection
Gilead Sciences
NCT07364448 RECRUITING A Study to Evaluate the Safety of Hydronidone Capsules in Patients With Liver Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.
NCT07413549 RECRUITING Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.
NCT06497504 ACTIVE NOT RECRUITING Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)
GlaxoSmithKline
NCT07135349 ACTIVE NOT RECRUITING A Phase II Clinical Study of BW-20507 in Combination With PEG-IFNα for the Treatment of Hepatitis B
Shanghai Argo Biopharmaceutical Co., Ltd.
NCT05832229 RECRUITING Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT07267208 NOT YET RECRUITING A Prospective Study to Evaluate the Efficacy and Safety of Entecavir ODT Conversion in Stable Liver Transplant Patients
Jongman Kim
NCT07069569 RECRUITING A Multicenter Study of AHB-137 Injection Combined With Other Hepatitis B Drugs
Ausper Biopharma Co., Ltd.
NCT06706310 ACTIVE NOT RECRUITING Evaluate TQ-A3334 Combined Nucleoside (Acid) Analogs in the First Treatment/Treatment of Chronic HBV Infection
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT07245953 ACTIVE NOT RECRUITING A Clinical Study of HT-101 and HT-102 in Patients With Chronic Hepatitis B Virus Infection
Suzhou HepaThera Biotech Co., Ltd.
NCT06425341 RECRUITING A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B
Fujian Shengdi Pharmaceutical Co., Ltd.
NCT07179575 RECRUITING Study of LW231 in Participants With Chronic Hepatitis B
Shanghai Longwood Biopharmaceuticals Co., Ltd.
NCT07190742 ACTIVE NOT RECRUITING A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of TVAX-008 Injection in Treated Patients With Chronic Hepatitis B
Grand Theravac Life Sciences (Nanjing) Co., Ltd.
NCT03038802 NOT YET RECRUITING A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection
Vaxine Pty Ltd
NCT07183306 ACTIVE NOT RECRUITING A Clinical Study of HT-101 and/or HT-102 in Patients With Chronic Hepatitis B Virus Infection
Suzhou HepaThera Biotech Co., Ltd.
NCT07179653 ACTIVE NOT RECRUITING A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of TVAX-008 Injection in Chronic Hepatitis B Patients
Grand Theravac Life Sciences (Nanjing) Co., Ltd.
NCT06154278 RECRUITING Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B
University of Maryland, Baltimore
NCT05771402 RECRUITING A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)
The Second Affiliated Hospital of Chongqing Medical University
NCT05769816 RECRUITING A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A)
The Second Affiliated Hospital of Chongqing Medical University
NCT05970289 ACTIVE NOT RECRUITING Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients
Brii Biosciences Limited
NCT07145268 NOT YET RECRUITING Zinc Sulphate in Treatment Fibrosis in HBV Patient Receiving Antiviral Therapy
Tanta University
NCT06887036 RECRUITING Methylene Blue Treatment of Chronic Hepatitis B Virus Infection
Fondazione Epatocentro Ticino
NCT06537414 ACTIVE NOT RECRUITING A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)
GlaxoSmithKline
NCT06513286 RECRUITING TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Michael Hoelscher
NCT06216470 RECRUITING Vaccinal Effect of HBsAg Monoclonal Ab VIR-3434 in Chronic Hepatitis B Infection [VISION]
University Health Network, Toronto
NCT06650852 RECRUITING A Study to Evaluate the Efficacy and Safety of Combination Therapy of BRII-179, BRII-835 and PEG-IFNα in Participants With Chronic Hepatitis B Virus (HBV) Infection (ENHANCE)
Brii Biosciences Limited
NCT04954859 ACTIVE NOT RECRUITING Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)
GlaxoSmithKline
NCT06263959 RECRUITING A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B
Fujian Akeylink Biotechnology Co., Ltd.
NCT06295328 RECRUITING From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT06338826 NOT YET RECRUITING Study Evaluating the Safety, in Terms of HBV Virological Control At 96 Weeks, of 2 Antiviral Treatment Relief Strategies, in Patients Co-infected with the HIV-1 and HBV Viruses
ANRS, Emerging Infectious Diseases
NCT06589518 NOT YET RECRUITING To Evaluate the Efficacy and Safety of Tenofovir Alafenamide Conversion in Liver Transplant Patients
Jongman Kim
NCT06491563 ACTIVE NOT RECRUITING Study to Investigate the Efficacy and Safety of Regimens Containing BRII-179, BRII-835, and PEG-IFNα Treating Chronic Hepatitis B Virus (HBV) Infection (ENRICH)
Brii Biosciences Limited
NCT06150014 ACTIVE NOT RECRUITING A Clinical Study of TQA3605 Tablets Monotherapy or in Combination With Nucleoside (Acid) Analogues in Treatment Naive and Treated Patients With Chronic Hepatitis B
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06618196 NOT YET RECRUITING Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age
LG Chem
NCT06452693 NOT YET RECRUITING A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis B
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT05304234 RECRUITING Liver Cancer Disparities in American Indian and Alaska Native Persons
University of Washington
NCT05453435 ACTIVE NOT RECRUITING Entecavir Prophylaxis for Hepatitis B Reactivation for CD20 Positive B-cell Lymphoma Patients With Resolved Hepatitis B (Negative Hepatitis B Surface Antigen, Positive Hepatitis B Core Antibody)
Sun Yat-sen University
NCT05597800 NOT YET RECRUITING Nivolumab/Ipilimumab and Chemotherapy Combination in Advanced NSCLC Patients With HIV, HBV, HCV and Long Covid Syndrome
Universita di Verona
NCT07630727 NOT YET RECRUITING Study of AHB-171 in Chronic Hepatitis B Participants
Ausper Biopharma Co., Ltd.
NCT05841095 ACTIVE NOT RECRUITING Evaluation of the Novel Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104
Erasmus Medical Center
NCT07635186 NOT YET RECRUITING A Study to Evaluate AHB-137 Injection in Treatment-naïve Participants With Chronic Hepatitis B
Ausper Biopharma Co., Ltd.
NCT07654283 NOT YET RECRUITING Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions
AusperBio Therapeutics Inc.
NCT05330455 TERMINATED Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection
GlaxoSmithKline
NCT06115993 COMPLETED A Study to Evaluate the Safety and Efficacy of AHB-137 in Healthy Participants and HBeAg-negative Chronic Hepatitis B (CHB) Patients
Ausper Biopharma Co., Ltd.
NCT05343481 COMPLETED Efficacy of VTP-300 in Chronic Hepatitis B Infection
Barinthus Biotherapeutics
NCT04980482 COMPLETED Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infection
Arbutus Biopharma Corporation
NCT04856085 COMPLETED Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection
Vir Biotechnology, Inc.
NCT05551273 COMPLETED Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04412863 COMPLETED Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infection
Vir Biotechnology, Inc.
NCT00536627 COMPLETED Efficacy and Tolerance of Naked DNA Vaccine in Patients With Chronic B Hepatitis
French National Agency for Research on AIDS and Viral Hepatitis
NCT03866187 TERMINATED Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection
GlaxoSmithKline
NCT03664518 COMPLETED to Evaluate the Efficacy and Safety of Eltrombopag for Immune Thrombocytopenia With Chronic HBV Infection
Institute of Hematology & Blood Diseases Hospital, China
NCT05612581 COMPLETED A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection
Vir Biotechnology, Inc.
NCT06644417 COMPLETED Clinical Study of TQA3605 Tablets Combined With Nucleoside (Acid) Analogs (NAs) Drugs Compared With NAs Drugs in the Treatment of Chronic Hepatitis B Virus (HBV) Infection
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT02065336 TERMINATED A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection
Arrowhead Pharmaceuticals
NCT02604199 TERMINATED A Multi-dose Study of ARC-520 in Patients With Hepatitis B 'e' Antigen (HBeAg) Negative, Chronic Hepatitis B Virus (HBV) Infection
Arrowhead Pharmaceuticals
NCT02604212 TERMINATED A Multi-dose Study of ARC-520 in Patients With Hepatitis B 'e' Antigen (HBeAg) Positive, Chronic Hepatitis B Virus Infection
Arrowhead Pharmaceuticals
NCT02738008 TERMINATED Extension Study of the Safety and Efficacy of Multi-dose Intravenous ARC-520 in Patients With Chronic Hepatitis B (HBV) Infection
Arrowhead Pharmaceuticals
NCT02577029 TERMINATED Study of ARC-520 With or Without Other Drugs Used in the Treatment of Chronic Chronic Hepatitis B Virus (HBV)
Arrowhead Pharmaceuticals
NCT05276297 COMPLETED A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapy
GlaxoSmithKline
NCT02349126 WITHDRAWN Study of ARC-520 in Patient With Chronic Hepatitis B Virus
Arrowhead Pharmaceuticals
NCT05961098 COMPLETED A Study of RBD1016 in CHB Participants
Suzhou Ribo Life Science Co. Ltd.
NCT04684914 TERMINATED HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)
Altimmune, Inc.
NCT02452528 TERMINATED Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B Virus
Arrowhead Pharmaceuticals
NCT03365947 COMPLETED Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)
Arrowhead Pharmaceuticals
NCT04225715 COMPLETED A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B
Hoffmann-La Roche
NCT04398706 COMPLETED Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants
Sanofi Pasteur, a Sanofi Company
NCT05345990 TERMINATED Treatment of Patients With Chronic Hepatitis B With Hepatitis B Immunoglobulins
Hannover Medical School
NCT06990776 WITHDRAWN A Clinical Trial to Evaluate the Efficacy and Safety of TQA3605 Tablets in Treatment-naive Chronic HBV-infected Subjects
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04891770 COMPLETED Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)
Gilead Sciences
NCT04544956 COMPLETED A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B
GlaxoSmithKline
NCT04439539 COMPLETED A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection
Janssen Research & Development, LLC
NCT04585789 COMPLETED A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus Infection
Janssen Research & Development, LLC
NCT05275023 COMPLETED An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants
Janssen Research & Development, LLC
NCT04710641 COMPLETED Radomised Phase II Study of MTL-CEBPA Plus Sorafenib or Sorafenib Alone
Mina Alpha Limited
NCT05637541 COMPLETED Evaluation of The Safety, Efficacy and Pharmacokinetic Characteristics of GST-HG141 Tablets
Fujian Akeylink Biotechnology Co., Ltd.
NCT04129554 COMPLETED A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection
Janssen Sciences Ireland UC
NCT03982186 COMPLETED A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infection
Janssen Sciences Ireland UC
NCT04426968 COMPLETED A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis B
Shanghai HEP Pharmaceutical Co., Ltd.
NCT05905458 COMPLETED A Phase II Clinical Study of the Efficacy and Safety of HRS9950 Tablets in Chronic Hepatitis B Patients Who Are Virologically Suppressed on Nucleoside or Nucleotide Analogues (NAs)
Chengdu Suncadia Medicine Co., Ltd.
NCT04465890 COMPLETED A Phase II Study of Subcutaneously Injected PD-L1 Antibody ASC22 in Chronic Hepatitis B Patients
Ascletis Pharmaceuticals Co., Ltd.
NCT05734807 COMPLETED A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia
Huahui Health
NCT03620474 COMPLETED Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis
Kiminori Kimura, MD
NCT04507269 COMPLETED Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China
Brii Biosciences Limited
NCT04778904 COMPLETED First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBV
Barinthus Biotherapeutics
NCT06245291 WITHDRAWN Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection
Arbutus Biopharma Corporation
NCT05404919 WITHDRAWN Utilization of Hepatitis B Virus NAT+ Donors for Hepatitis B Vaccinated Lung Transplant Candidates
University of Pennsylvania
NCT05244057 COMPLETED A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients
Shanghai HEP Pharmaceutical Co., Ltd.
NCT04667104 COMPLETED A Study of JNJ-73763989, JNJ-56136379, Nucleos(t)Ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection
Janssen Research & Development, LLC
NCT04536532 TERMINATED Evaluation HEC121120 Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study
Sunshine Lake Pharma Co., Ltd.
NCT04147208 COMPLETED Evaluate the Safety, Tolerability, and Antiviral Activity of GLS4 With Ritonavir in Patients With Chronic HBV Infection
Sunshine Lake Pharma Co., Ltd.
NCT04749368 COMPLETED Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) Infection
Brii Biosciences Limited
NCT04676724 COMPLETED Study of Sequential GSK3228836 and Peginterferon Treatment in Participants With Chronic Hepatitis B (CHB)
GlaxoSmithKline
NCT05107778 COMPLETED Study to Evaluate Safety and Efficacy of ASC42 Combined With ETV and PEG-IFN α-2a in Subjects With HBV
Ascletis Pharmaceuticals Co., Ltd.
NCT04114890 COMPLETED Tenofovir in Pregnancy to Prevent Mother to Child Transmission of Hepatitis B.
University of Oxford
NCT05005507 TERMINATED A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection
Janssen Research & Development, LLC
NCT04289987 COMPLETED A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B Vaccine
CHA Vaccine Institute Co., Ltd.
NCT05760703 TERMINATED Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis B
Staidson (Beijing) Biopharmaceuticals Co., Ltd
NCT05760781 TERMINATED To Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis B
Staidson (Beijing) Biopharmaceuticals Co., Ltd
NCT02693652 COMPLETED A Study to Evaluate the Safety and Efficacy of Therapeutic Hepatitis B Vaccine
CHA Vaccine Institute Co., Ltd.
NCT04820686 TERMINATED A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection
Assembly Biosciences
NCT03905655 COMPLETED Study of Nitazoxanide Compared to Placebo in Subjects With HBeAG-Negative Chronic Hepatitis B
Romark Laboratories L.C.
NCT05674448 TERMINATED A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With Chronic Hepatitis B and Hepatitis D Co-infection
Huahui Health
NCT04781647 TERMINATED A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus Infection
Assembly Biosciences
NCT05839639 COMPLETED A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With HBeAg-Negative Chronic Hepatitis B Treated With Nucleos(t)Ide Reverse Transcriptase Inhibitors
Huahui Health
NCT03625102 COMPLETED A Randomized, Double-Blind Trial of Antroquinonol in Patients With Chronic Hepatitis B
Golden Biotechnology Corporation
NCT04046107 WITHDRAWN Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04449029 COMPLETED A Study of GSK3228836 in Participants With Chronic Hepatitis B (CHB)
GlaxoSmithKline
NCT03780543 TERMINATED A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patients
Assembly Biosciences
NCT02995005 COMPLETED Tenofovir in Early Pregnancy to Prevent Mother-to-child Transmission of Hepatitis B Virus
Johns Hopkins Bloomberg School of Public Health
NCT05019040 COMPLETED Study of the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of PA1010 in HBV Patients
Zhejiang Palo Alto Pharmaceuticals, Inc.
NCT04847440 TERMINATED A Study of Safety and Efficacy of ATI-2173 in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection and in Subjects With Hepatitis D Virus Coinfection
Antios Therapeutics, Inc
NCT03361956 COMPLETED An Efficacy, Safety, and Pharmacokinetics Study of JNJ-56136379 in Participants With Chronic Hepatitis B Virus Infection
Janssen Sciences Ireland UC
NCT04465916 TERMINATED Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD)
Enyo Pharma
NCT04454567 TERMINATED A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase Inhibitors
Assembly Biosciences
NCT04398134 TERMINATED A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infection
Assembly Biosciences
NCT04365933 COMPLETED A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir
Enyo Pharma
NCT02499562 COMPLETED A Phase II Clinical Trial of Hydronidone Capsules(F351) in Patients With Liver Fibrosis Induced by HBV Chronic Hepatitis
Shanghai Genomics, Inc.
NCT02862548 COMPLETED Efficacy and Safety of Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF)-Containing Regimens in Participants With Chronic Hepatitis B Virus (HBV) Infection and Stage 2 or Greater Chronic Kidney Disease Who Have Received a Liver Transplant
Gilead Sciences
NCT05238844 TERMINATED A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection
Antios Therapeutics, Inc
NCT03615066 COMPLETED Study to Evaluate the Safety, Tolerability, and Antiviral Activity of Selgantolimod (Formerly GS-9688) in Viremic Adult Participants With Chronic Hepatitis B (CHB) Who Are Not Currently on Treatment
Gilead Sciences
NCT05326152 COMPLETED Intralesional Versus Intramuscular Hepatitis B Vaccine Immunotherapy for Warts
Zagazig University
NCT03575208 WITHDRAWN Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03434353 TERMINATED Study to Evaluate the Safety and Antiviral Activity of Inarigivir Soproxil (Formerly: GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB)
Gilead Sciences
NCT03672188 COMPLETED Study of VIR-2218 in Healthy Subjects and Patients With Chronic Hepatitis B
Vir Biotechnology, Inc.
NCT03180619 COMPLETED Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV)
Gilead Sciences
NCT03312023 COMPLETED Ledipasvir/Sofosbuvir for Hepatitis B Virus Infection
University of Maryland, Baltimore
NCT03491553 COMPLETED Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis B
Gilead Sciences
NCT02981602 COMPLETED Safety, Tolerability, Pharmacokinetics and Antiviral Activity of IONIS-HBVRx in Treatment-Naïve Patients With Chronic HBV Infection
GlaxoSmithKline
NCT03546621 COMPLETED A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D
Hepatera Ltd.
NCT02888106 COMPLETED Myrcludex B in Combination With Peginterferon Alfa-2a Versus Peginterferon Alfa-2a Alone in Patients With Chronic Viral Hepatitis B With Delta-agent
Hepatera Ltd.
NCT03294798 COMPLETED Study of Recombinant Human Serum Albumin/Interferon alpha2b Fusion Protein in Hepatitis B Patient
Tianjin SinoBiotech Ltd.
NCT03576066 COMPLETED A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection
Assembly Biosciences
NCT03577171 COMPLETED A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)
Assembly Biosciences
NCT01935635 COMPLETED A Clinical Trial on HB-Vac Activated-DCs Combined With Peg-IFN or NAs in CHB
Third Affiliated Hospital, Sun Yat-Sen University
NCT02166047 COMPLETED Study To Evaluate Safety and Efficacy of Vesatolimod for the Treatment of Chronic Hepatitis B Virus in Virally-Suppressed Participants
Gilead Sciences
NCT03020745 COMPLETED A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3389404 in Chronic Hepatitis B (CHB) Subjects
GlaxoSmithKline
NCT03638076 COMPLETED The Safety, Antiviral Activity, and Pharmacokinetics of Morphothiadine Mesilate Capsules
Sunshine Lake Pharma Co., Ltd.
NCT04023721 TERMINATED Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor
F-star Therapeutics, Inc.
NCT04059198 TERMINATED Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus
F-star Therapeutics, Inc.
NCT01453998 COMPLETED Safety and Immunogenicity of a Booster Dose of New Formulations of GlaxoSmithKline Biologicals' DTPa-HBV-IPV/Hib Vaccine (GSK217744)
GlaxoSmithKline
NCT01125696 COMPLETED Safety Study of a Tenofovir-containing Drug Regimen for the Prevention of Mother-to-child Transmission of HIV and HBV
Centers for Disease Control and Prevention
NCT02579382 COMPLETED Study to Evaluate the Safety, Tolerability, and Efficacy of Vesatolimod in Combination With Tenofovir Disoproxil Fumarate (TDF) in Adults With Chronic Hepatitis B (CHB) Infection Who Are Currently Not Being Treated
Gilead Sciences
NCT03932513 TERMINATED Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients
F-star Therapeutics, Inc.
NCT03115736 COMPLETED TAF for HIV-HBV With Renal Dysfunction
Insel Gruppe AG, University Hospital Bern
NCT01524679 COMPLETED Peg-interferon ADDed to an Ongoing Nucleos(t)Ide Based Treatment in Patients With Chronic Hepatitis B to Induce Decrease of HBs-Antigen
Johannes Gutenberg University Mainz
NCT02751996 COMPLETED A Study Evaluating the Safety, Pharmacokinetics, and Antiviral Efficacy of SB 9200 in Subjects Infected With Chronic HBV
F-star Therapeutics, Inc.
NCT01171989 COMPLETED Immunogenicity and Safety Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine Administered as a Booster Dose
GlaxoSmithKline
NCT02289300 WITHDRAWN A Study to Evaluate a Study Drug, DCB-BO1202, for Alleviating Liver Fibrosis in Liver Cancer Patients
A2 Healthcare Taiwan Corporation
NCT00970307 COMPLETED Immunogenicity and Safety Study of GSK Biologicals' GSK2202083A Vaccine in Healthy Infants at 2, 3 and 4 Months of Age
GlaxoSmithKline
NCT01943799 COMPLETED Safety and Efficacy of GS-4774 for the Treatment of Chronic Hepatitis B
Gilead Sciences
NCT00869778 COMPLETED Phase 2 Trial of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis B
Chongqing Jiachen Biotechnology Ltd.
NCT01106092 COMPLETED Study to Evaluate the Immunogenicity and Reactogenicity of a Booster Dose of GSK2036874A Vaccine in Healthy Toddlers
GlaxoSmithKline
NCT02565719 COMPLETED REP 2139-Mg and REP 2165-Mg Combination Therapy in Chronic Hepatitis B Infection
Replicor Inc.
NCT02364336 COMPLETED Add-on Peginterferon Following Nucleos(t)Ide Analogue Treatment
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02862106 COMPLETED Second Stage:Open-label Study of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis B
Chongqing Jiachen Biotechnology Ltd.
NCT01326546 COMPLETED Therapeutic Hepatitis B Vaccine (Mimogen-based) Joint Entecavir in Treating Chronic Hepatitis B Patients
Chongqing Jiachen Biotechnology Ltd.
NCT02174276 COMPLETED Safety and Efficacy of GS-4774 in Combination With Tenofovir Disoproxil Fumarate (TDF) for the Treatment of Participants With Chronic Hepatitis B (CHB) and Who Are Currently Not on Treatment
Gilead Sciences
NCT02726789 COMPLETED Combination Treatment With REP 2139-Ca and Pegasys in Patients With Chronic Hepatitis B
Replicor Inc.
NCT03415672 COMPLETED Hepatitis B Vaccine for Non-responders
Maastricht University Medical Center
NCT01777295 COMPLETED Development of Read-outs in Healthy, Hepatitis B Virus Naive Adults Vaccinated With the Hepatitis B Surface Antigen (HBsAg) in Combination With a GlaxoSmithKline (GSK) Biologicals' Adjuvant System
GlaxoSmithKline
NCT02338674 COMPLETED TDF and LdT in Immune-tolerant CHB Patients Awaiting Assisted Reproduction
Fuzhou General Hospital
NCT02881008 COMPLETED Myrcludex B vs Entecavir in Patients With HBeAg Negative Chronic Hepatitis B
Hepatera Ltd.
NCT01248884 COMPLETED Safety and Immunogenicity of New Formulations of GlaxoSmithKline Biologicals' DTPa-HBV-IPV/Hib Vaccine (GSK217744)
GlaxoSmithKline
NCT01090453 COMPLETED Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants
GlaxoSmithKline
NCT00805389 COMPLETED Study to Compare the Efficacy of GSK Biologicals' Adjuvants in Combination With the Antigen of the Hepatitis B Vaccine
GlaxoSmithKline
NCT03109730 COMPLETED Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis B
Assembly Biosciences
NCT02631096 COMPLETED Study of ARB-001467 in Subjects With Chronic HBV Infection Receiving Nucleos(t)Ide Analogue Therapy
Arbutus Biopharma Corporation
NCT02391805 COMPLETED A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection
Hoffmann-La Roche
NCT00871741 TERMINATED Feasibility Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants at 3, 5 and 11 Months of Age.
GlaxoSmithKline
NCT00627458 COMPLETED Immunogenicity and Reactogenicity of a Booster Dose of GSK Bio's DTPa-HBV-IPV/Hib Vaccine
GlaxoSmithKline
NCT03125213 WITHDRAWN A Study Evaluating AL-3778 in Combination With Peginterferon Alpha-2a in Chronic Hepatitis B Subjects
Alios Biopharma Inc.
NCT02233075 COMPLETED REP 2139-Ca / Pegasys™ Combination Therapy in Hepatitis B / Hepatitis D Co-infection
Replicor Inc.
NCT00936715 COMPLETED Rollover Protocol Continued Access to Emtricitabine/Tenofovir Disoproxil Fumarate for Adults in United States
Gilead Sciences
NCT01706575 COMPLETED A Study of Pegasys (Peginterferon Alfa-2a) Added to Nucleos(t)Ide Analogue Treatment in Participants With HBeAg-Negative Chronic Hepatitis B Genotype D Showing Stable Hepatitis B Virus (HBV) Deoxyribonucleic Acid (DNA) Suppression
Hoffmann-La Roche
NCT02332473 COMPLETED A Prospective Study of Combination of Peginterferon Alfa-2b (40kD, Y-shape) and GM-CSF in Chronic Hepatitis B
Xiamen Amoytop Biotech Co., Ltd.
NCT01217632 TERMINATED A Study of FG-3019 in Subjects With Liver Fibrosis Due to Chronic Hepatitis B Infection
Kyntra Bio
NCT02304315 COMPLETED A Phase 2 Study of GC1102 (Recombinant Hepatitis B Immunoglobulin) in HBV-related Liver Transplant Recipients
Green Cross Corporation
NCT02646163 COMPLETED Therapeutic Safety and Efficacy of REP 9AC (REP 2055) in HBV or HCV Infected Patients
Replicor Inc.
NCT02646189 COMPLETED Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patients
Replicor Inc.
NCT01204762 COMPLETED Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen
Bristol-Myers Squibb
NCT01124591 COMPLETED Brief Intervention for Drug Misuse in the Emergency Department
Rhode Island Hospital
NCT02366208 COMPLETED Phase II Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg Positive Chronic Hepatitis B
Jiangsu Hansoh Pharmaceutical Co., Ltd.
NCT01997944 COMPLETED Recombinant Human Serum Albumin/Interferon alpha2a Fusion Protein Phase Ib Study in Chronic Hepatitis B Patients
Beijing Bio-Fortune Ltd.
NCT01334567 COMPLETED Rollover Protocol Continued Access to Tenofovir Disoproxil Fumarate (TDF) for Subjects in Taiwan
Gilead Sciences
NCT01143662 COMPLETED Efficacy and Safety of Ypeginterferon Alfa-2b in HBeAg Positive Chronic Hepatitis B
Xiamen Amoytop Biotech Co., Ltd.
NCT01026610 COMPLETED Safety and Efficacy Study of LB80380 in the Treatment-naive Patients of Chronic Hepatitis B
LG Life Sciences
NCT00804622 COMPLETED Effects of Telbivudine and Tenofovir Disproxil Fumarate on the Kinetics of Hepatitis B Virus DNA in Chronic Hepatitis B (CHB)
The University of Hong Kong
NCT00964665 TERMINATED Pharmacokinetic/Pharmacodynamic of Albinterferon Alfa-2b in Chronic Hepatitis B, eAg+, Infection Subjects
Novartis Pharmaceuticals