Mastocytosis Clinical Trial Landscape
Mastocytosis is being studied across 28 clinical trials registered since 2008, with 8 programs currently active. The competitive pipeline includes 1 active Phase 3 trials, 4 active Phase 2 trials, and 2 active Phase 1 trials.
Top industry sponsors include Blueprint Medicines Corporation, Cogent Biosciences, Inc., MacroGenics.
Trial activity
Sponsor activity
Who is running trials now — green active, blue completed, red failed/terminated.
How the field has grown
New-trial starts peaked in 2020 (4 registered); 2025 saw 0. The right-hand chart shows median Phase 3 enrollment by start year — the number in parentheses is that year's Phase 3 trial count (2 in total), so single-trial years (and years with no Phase 3 starts) are obvious. Both are by trial start date; the current year is partial.
New trials started by year
TheraRadar.com
Median Phase 3 enrollment by start year
TheraRadar.com
Full trial pipeline
Every active and completed trial across Phase 1–4, with enrollment analytics. Sortable, filterable, exportable with Pro.
Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only