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Data updated: Jun 17, 2026

CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER (calcium chloride)

Other Approved 2000-01-28

Ringer’s Injection helps patients who require a supplemental source of water and electrolytes. It is used for both adult and pediatric populations to maintain proper fluid balance and hydration. This solution provides essential minerals that support various physiological processes, including heart function and nerve conduction.

Source: FDA Label • Pfizer

How CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER Works

This injection works by replenishing essential electrolytes and water to maintain the body's internal environment. Sodium and chloride help regulate fluid distribution and acid-base balance, while potassium and calcium are vital for nerve signaling, muscle contractions, and heart function.

1
Indication
--
Phase 3 Trials
26
Years on Market

Details

Status
Prescription
First Approved
2000-01-28
Routes
INJECTION
Dosage Forms
INJECTABLE

Companies

Active Ingredient: CALCIUM CHLORIDE

CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER Approval History

2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
6 FDA actions from 2000 to 2023
May 2023 SUPPL
Label · Labeling
Aug 2021 SUPPL
Mfg · Manufacturing (CMC)
Jul 2018 SUPPL
Label · Labeling

What CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER Treats

2 indications

CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER is approved for 2 conditions since its original approval in 2000. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Water deficiency
  • Electrolyte deficiency
Source: FDA Label

Drugs Similar to CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER

3 of 19

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

CARDIOPLEGIC IN PLASTIC CONTAINER
CALCIUM CHLORIDE
2 shared
Baxter
Shared indications:
Water deficiencyElectrolyte deficiency
DELFLEX W/ DEXTROSE 2.5% LOW MAGNESIUM IN PLASTIC CONTAINER
CALCIUM CHLORIDE
2 shared
Fresenius Kabi
Shared indications:
Electrolyte deficiencyWater deficiency
DELFLEX W/ DEXTROSE 4.25% LOW MAGNESIUM LOW CALCIUM IN PLASTIC CONTAINER
CALCIUM CHLORIDE
2 shared
Fresenius Kabi
Shared indications:
Water deficiencyElectrolyte deficiency
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Clinical Trial Registry

7 trials
Trial Sponsor ID Phase Status Title
NCT07550413 20042026 Ph 2 not yet recruiting Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section
NCT03772990 ICARUS 21/2019 Ph 4 completed Calcium Administration in Cardiac Surgery
NCT05027048 CALBLOC results posted 62206 MRTG-02-15-2022-Ansari, YIG-2020 Ph 3 completed Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery
NCT04153435 COCA results posted 00002 2019-003387-46 Ph 2 completed Calcium for Out-of-Hospital Cardiac Arrest
NCT03867383 results posted 43076 Ph 1, Ph 2 completed Calcium Chloride for Prevention of Uterine Atony During Cesarean
NCT01941914 AA1310 Ph 1 completed Calcium Electroporation for the Treatment of Keloids
NCT00955266 results posted 2009-P-000052 Ph 4 terminated A Trial of Intravenous Calcium and Myocardial Diastolic Dysfunction During Separation From Cardiopulmonary Bypass
🔬

Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER FDA Label Details

Indications & Usage

FDA Label (PDF)

CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER is indicated for the treatment of Water deficiency; Electrolyte deficiency.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.