TheraRadar
Data updated: Jun 28, 2026

DYNACIRC CR (isradipine) · GSK

Cardiovascular Approved 1994-06-01

DYNACIRC CR is FDA-approved to treat 1 condition (same as ISRADIPINE).

Source: FDA Label
1
Indication
--
Phase 3 Trials
32
Years on Market

Details

Status
Discontinued
First Approved
1994-06-01
Routes
ORAL
Dosage Forms
TABLET, EXTENDED RELEASE

Companies

Active Ingredient: ISRADIPINE

DYNACIRC CR Approval History

1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
18 FDA actions from 1994 to 2005
May 2005 SUPPL
Label · Labeling
Jun 2002 SUPPL
Mfg · Manufacturing (CMC)
Apr 2002 SUPPL
Mfg · Manufacturing (CMC)

What DYNACIRC CR Treats

1 indications

DYNACIRC CR is approved for 1 conditions since its original approval in 1994. These indications span multiple therapeutic areas including oncology, immunology, and more.

Same approved indications as ISRADIPINE (same active ingredient).

Source: FDA Label
📋

Clinical Trial Registry

3 trials
Trial Sponsor ID Phase Status Title
NCT02168842 results posted STEADY-PD III U01NS080818-01A1, U01NS080840-01A1 Ph 3 completed Efficacy of Isradipine in Early Parkinson Disease
NCT01895270 results posted R21DA035325 R21DA035325 Ph 1, Ph 2 completed Improving Buprenorphine Detoxification Outcomes With Isradipine
NCT01784666 Isradipine results posted 2012-P-002449/1 Ph 2 terminated Adjunctive Isradipine for the Treatment of Bipolar Depression
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Active Pipeline

Pro

Ongoing clinical trials by development phase

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Key Completed Trials

Pro

Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

DYNACIRC CR FDA Label Details

Indications & Usage

DYNACIRC CR is FDA-approved to treat 1 condition — same approved indications as ISRADIPINE.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.