Data updated: Jun 28, 2026
MEPERIDINE HYDROCHLORIDE
Pain
Approved 1942-11-10
18
Indications
--
Phase 3 Trials
83
Years on Market
Details
- Status
- Prescription
- First Approved
- 1942-11-10
- Routes
- INJECTION, ORAL
- Dosage Forms
- INJECTABLE, TABLET, SYRUP
Companies
ABBOTT WEST-WARD PHARMS INT Baxter IGI LABS INC WATSON LABS INC Sun Pharma Hikma EPIC PHARMA LLC Pfizer SPECGX LLC GENUS PARKE DAVIS STRIDES PHARMA INTL INTL MEDICATION Teva DURAMED PHARMS BARR
Active Ingredient: MEPERIDINE HYDROCHLORIDE
Website: ↗
MEPERIDINE HYDROCHLORIDE Approval History
1973
1974
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
455 FDA actions from 1972 to 2026
Jun 2026 SUPPL
Update · REMS
May 2026 SUPPL
Label · Labeling
Dec 2025 SUPPL
Label · Labeling
Oct 2024 SUPPL
Update
Oct 2024 SUPPL
Label
Aug 2024 SUPPL
Label
Jul 2024 SUPPL
Label
May 2024 SUPPL
Label
Apr 2024 SUPPL
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Apr 2024 SUPPL
Label
Apr 2024 SUPPL
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Mar 2024 SUPPL
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Dec 2023 SUPPL
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Dec 2023 SUPPL
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Dec 2023 SUPPL
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Dec 2023 SUPPL
Label
Aug 2023 SUPPL
Label
Jul 2023 SUPPL
Label
Mar 2021 SUPPL
Label
Dec 2020 SUPPL
Label
Oct 2019 SUPPL
Label
Oct 2019 SUPPL
Label
Sep 2018 SUPPL
Update
Apr 2017 SUPPL
Label
May 2015 SUPPL
Label
Jan 2015 SUPPL
Label
Oct 2013 SUPPL
Label
Aug 2012 SUPPL
Label
Mar 2012 SUPPL
Label
Oct 2011 SUPPL
Label
May 2011 SUPPL
Label
May 2011 SUPPL
Label
Sep 2009 SUPPL
Label
Jul 2009 SUPPL
Label
Jun 2009 ORIGINAL
Update
Jun 2009 SUPPL
Label
Apr 2009 SUPPL
Label
Sep 2006 SUPPL
Label
Nov 2005 SUPPL
Label
Oct 2005 SUPPL
Label
Sep 2005 SUPPL
Label
Jul 2005 SUPPL
Label
Apr 2005 SUPPL
Label
Dec 2004 SUPPL
Label
Sep 2004 SUPPL
Label
Aug 2004 SUPPL
Label
Jun 2004 SUPPL
Label
Mar 2004 SUPPL
Label
Apr 2002 SUPPL
Mfg
Jul 2001 SUPPL
Mfg
Jul 2001 SUPPL
Mfg
Apr 2001 SUPPL
Mfg
Oct 2000 SUPPL
Mfg
Mar 2000 SUPPL
Mfg
Dec 1999 SUPPL
Mfg
Jun 1999 SUPPL
Mfg
May 1999 SUPPL
Mfg
Mar 1999 SUPPL
Mfg
Feb 1999 SUPPL
Mfg
Feb 1999 SUPPL
Mfg
Dec 1998 SUPPL
Mfg
Nov 1998 SUPPL
Mfg
Aug 1998 SUPPL
Mfg
Nov 1997 SUPPL
Mfg
Oct 1997 SUPPL
Mfg
Jun 1997 ORIGINAL
Update
Mar 1997 ORIGINAL
Update
Jan 1997 SUPPL
Mfg
Jan 1997 SUPPL
Mfg
Dec 1996 SUPPL
Mfg
Oct 1996 SUPPL
Mfg
Aug 1996 SUPPL
Mfg
Aug 1996 SUPPL
Mfg
Apr 1996 SUPPL
Mfg
Jan 1996 SUPPL
Mfg
Sep 1995 SUPPL
Mfg
Aug 1995 SUPPL
Label
Jul 1995 SUPPL
Mfg
Dec 1994 SUPPL
Mfg
Mar 1994 SUPPL
Label
Jul 1993 SUPPL
Mfg
May 1992 SUPPL
Label
Apr 1992 SUPPL
Mfg
Mar 1992 ORIGINAL
Update
Mar 1992 SUPPL
Label
Mar 1992 SUPPL
Label
Oct 1991 SUPPL
Label
Sep 1991 SUPPL
Label
Aug 1991 SUPPL
Mfg
Jul 1991 SUPPL
Label
Apr 1991 SUPPL
Label
Dec 1990 SUPPL
Label
Apr 1990 SUPPL
Label
Feb 1990 SUPPL
Mfg
Jan 1990 SUPPL
Label
Jan 1990 SUPPL
Mfg
Oct 1989 SUPPL
Label
Oct 1989 SUPPL
Label
Sep 1989 SUPPL
Label
Aug 1989 SUPPL
Label
Jul 1989 SUPPL
Label
Mar 1989 SUPPL
Label
Dec 1988 SUPPL
Label
Sep 1988 SUPPL
Mfg
May 1988 SUPPL
Label
Nov 1987 SUPPL
Mfg
Apr 1987 SUPPL
Mfg
Mar 1987 SUPPL
Mfg
Nov 1986 SUPPL
Mfg
Aug 1986 SUPPL
Mfg
May 1985 SUPPL
Mfg
Apr 1985 SUPPL
Mfg
Jan 1985 ORIGINAL
Update
Sep 1984 ORIGINAL
Update
Jul 1984 ORIGINAL
Update
Jun 1984 ORIGINAL
Update
Jan 1984 SUPPL
Mfg
Dec 1983 SUPPL
Mfg
Oct 1983 SUPPL
Mfg
Oct 1983 SUPPL
Mfg
Mar 1983 SUPPL
Mfg
Oct 1976 ORIGINAL
Update
May 1976 ORIGINAL
Update
Jan 1975 ORIGINAL
Update
Jul 1973 ORIGINAL
Update
Apr 1972 ORIGINAL
Update
What MEPERIDINE HYDROCHLORIDE Treats
18 FDA approvalsOriginally approved for its first indication in 1972 . Covers 18 distinct patient populations.
- Other (18)
Other
(18 approvals)- • Approved indication (Apr 1972)
- • Approved indication (Jul 1973)
- • Approved indication (Jan 1975)
- • Approved indication (May 1976)
- • Approved indication (Oct 1976)
- • Approved indication (Jun 1984)
- • Approved indication (Jul 1984)
- • Approved indication (Sep 1984)
- • Approved indication (Jan 1985)
- • Approved indication (Mar 1992)
- • Approved indication (Mar 1997)
- • Approved indication (Jun 1997)
- • Approved indication (Dec 1998)Label Letter
- • Approved indication (May 1999)Letter
- • Approved indication (Oct 1999)Letter
- • Approved indication (Jun 2000)Label Letter
- • Approved indication (Aug 2002)Letter
- • Approved indication (Jun 2009)
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Pro Active Pipeline
Ongoing clinical trials by development phase
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Pro Key Completed Trials
Completed studies with published results, ranked by significance
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Trial Timeline
Full development history with FDA approval milestones
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Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
MEPERIDINE HYDROCHLORIDE FDA Label Details
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Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.