TheraRadar
Data updated: Jun 28, 2026

RYTHMOL SR (propafenone hydrochloride) · GSK

Cardiovascular Approved 2003-09-04

RYTHMOL SR is FDA-approved to treat 5 conditions (same as PROPAFENONE HYDROCHLORIDE).

1
Indication
--
Phase 3 Trials
22
Years on Market

Details

Status
Discontinued
First Approved
2003-09-04
Routes
ORAL
Dosage Forms
CAPSULE, EXTENDED RELEASE

Companies

Active Ingredient: PROPAFENONE HYDROCHLORIDE

RYTHMOL SR Approval History

2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
24 FDA actions from 2003 to 2018
Nov 2018 SUPPL
Label · Labeling
Jul 2014 SUPPL
Mfg · Manufacturing (CMC)
Sep 2013 SUPPL
Mfg · Manufacturing (CMC)

What RYTHMOL SR Treats

5 indications

RYTHMOL SR is approved for 5 conditions since its original approval in 2003. These indications span multiple therapeutic areas including oncology, immunology, and more.

Same approved indications as PROPAFENONE HYDROCHLORIDE (same active ingredient).

Source: FDA Label
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

RYTHMOL SR FDA Label Details

Indications & Usage

FDA Label (PDF)

RYTHMOL SR is FDA-approved to treat 5 conditions — same approved indications as PROPAFENONE HYDROCHLORIDE.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.