TheraRadar
Data updated: Jun 28, 2026

XOPENEX (levalbuterol hydrochloride) · Hikma

Respiratory Approved 1999-03-25

XOPENEX is FDA-approved to treat 2 conditions (same as LEVALBUTEROL HYDROCHLORIDE).

3
Indications
--
Phase 3 Trials
27
Years on Market

Details

Status
Discontinued
First Approved
1999-03-25
Routes
INHALATION
Dosage Forms
SOLUTION

Companies

Active Ingredient: LEVALBUTEROL HYDROCHLORIDE

XOPENEX Approval History

2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
80 FDA actions from 1999 to 2019 · 2 indication expansions
Jan 2019 SUPPL
Label · Labeling
Mar 2015 SUPPL
Label · Labeling
Jan 2015 SUPPL
Efficacy

What XOPENEX Treats

2 indications

XOPENEX is approved for 2 conditions since its original approval in 1999. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Bronchospasm
  • Obstructive Airway Disease

Same approved indications as LEVALBUTEROL HYDROCHLORIDE (same active ingredient).

Source: FDA Label
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

XOPENEX FDA Label Details

Indications & Usage

FDA Label (PDF)

XOPENEX is FDA-approved to treat 2 conditions — same approved indications as LEVALBUTEROL HYDROCHLORIDE.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.