TheraRadar

argenx

Pre-Approval PRO BETA
72
Total Trials
32
Phase 3
28
Phase 2
25
Recruiting
815
Score

Pipeline by Phase

Phase 3
32
Phase 2
28
Phase 1
17

Therapeutic Focus

Generalized Myasthenia Gravis Healthy Volunteers Primary Immune Thrombocytopenia gMG Chronic Inflammatory Demyelinating Polyneuropathy

Clinical Trials (72)

NCT06920004 Phase 3 RECRUITING

A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP

Started: 8/22/2025

NCT07091630 Phase 3 RECRUITING

A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP

Started: 9/16/2025

NCT06544499 Phase 3 RECRUITING

A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

Started: 10/18/2024

NCT07570316 Phase 3 NOT YET RECRUITING

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease

Started: 6/1/2026

NCT05979441 Phase 3 ENROLLING BY INVITATION

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy

Started: 9/12/2023

NCT06684847 Phase 3 ACTIVE NOT RECRUITING

A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

Started: 1/15/2025

NCT06307626 Phase 3 TERMINATED

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease.

Started: 3/28/2024

NCT04225156 Phase 3 COMPLETED

A Long-term Study to Assess the Safety and Efficacy of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP).

Started: 6/2/2020

NCT06307613 Phase 3 TERMINATED

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease

Started: 3/27/2024

NCT06742190 Phase 3 ACTIVE NOT RECRUITING

A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy

Started: 12/18/2024

NCT05681481 Phase 3 TERMINATED

A Phase 3 Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid

Started: 3/22/2023

NCT04818671 Phase 3 COMPLETED

Evaluating the Long-Term Safety and Tolerability of Efgartigimod PH20 SC Administered Subcutaneously in Patients With Generalized Myasthenia Gravis

Started: 4/26/2021

NCT04812925 Phase 3 ACTIVE NOT RECRUITING

A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia

Started: 11/17/2021

NCT06558279 Phase 3 ACTIVE NOT RECRUITING

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia Gravis

Started: 9/18/2024

NCT04980495 Phase 3 COMPLETED

An Open-label Study to Investigate the Clinical Efficacy of Different Dosing Regimens of Efgartigimod IV in Patients With Generalized Myasthenia Gravis

Started: 12/16/2021

NCT06298552 Phase 3 ACTIVE NOT RECRUITING

A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis

Started: 4/16/2024

NCT04598477 Phase 3 TERMINATED

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)

Started: 7/15/2021

NCT04188379 Phase 3 COMPLETED

A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP).

Started: 12/16/2019

NCT04687072 Phase 3 COMPLETED

A Study to Evaluate the Efficacy and Safety of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia

Started: 12/16/2020

NCT04598451 Phase 3 COMPLETED

A Study to Assess the Efficacy and Safety of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)

Started: 12/1/2020

NCT03770403 Phase 3 COMPLETED

A Safety and Tolerability Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness.

Started: 3/1/2019

NCT04735432 Phase 3 COMPLETED

Evaluating the Pharmacodynamic Noninferiority of Efgartigimod PH20 SC Administered Subcutaneously as Compared to Efgartigimod Administered Intravenously in Patients With Generalized Myasthenia Gravis

Started: 2/5/2021

NCT03669588 Phase 3 COMPLETED

An Efficacy and Safety Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness

Started: 8/22/2018

NCT04274452 Phase 3 WITHDRAWN

A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP)

Started: 6/29/2020

NCT07596849 Phase 3 NOT YET RECRUITING

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease.

Started: 6/1/2026

NCT06392386 Phase 2 RECRUITING

A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis

Started: 6/28/2024

NCT06655155 Phase 2 RECRUITING

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

Started: 11/11/2024

NCT07284420 Phase 2 RECRUITING

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

Started: 12/19/2025

NCT07287982 Phase 2 RECRUITING

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

Started: 12/19/2025

NCT07194850 Phase 2 RECRUITING

A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)

Started: 10/20/2025

NCT06503731 Phase 2 RECRUITING

A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR)

Started: 8/30/2024

NCT04833894 Phase 2 RECRUITING

Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis

Started: 10/26/2021

NCT07583641 Phase 2 NOT YET RECRUITING

A Study to Learn About How Well the Medicine Efgartigimod Works to Treat Autoimmune Encephalitis In Children 12 Years or Older and Adults

Started: 7/13/2026

NCT05225675 Phase 2 COMPLETED

A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy

Started: 3/31/2022

NCT05374590 Phase 2 ENROLLING BY INVITATION

Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis

Started: 8/18/2022

NCT06441682 Phase 2 ACTIVE NOT RECRUITING

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)

Started: 10/23/2024

NCT05907096 Phase 2 ACTIVE NOT RECRUITING

ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft Function

Started: 2/17/2024

NCT05405361 Phase 2 ACTIVE NOT RECRUITING

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy

Started: 1/18/2023

NCT06203457 Phase 2 COMPLETED

Open-Label Extension Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren's Syndrome

Started: 11/29/2023

NCT05810948 Phase 2 COMPLETED

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)

Started: 2/21/2023

NCT05267600 Phase 2 COMPLETED

A Phase 2/3 Study of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid

Started: 6/9/2022

NCT05918978 Phase 2 TERMINATED

Open Label Extension of Efgartigimod in Adults With Post-COVID-19 POTS

Started: 6/20/2023

NCT06284954 Phase 2 ACTIVE NOT RECRUITING

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis

Started: 8/20/2024

NCT05523167 Phase 2 ACTIVE NOT RECRUITING

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

Started: 10/12/2022

NCT05817669 Phase 2 COMPLETED

A Study of the Safety and Effectiveness of Efgartigimod in Patients With Primary Sjögren's Syndrome (pSS)

Started: 4/4/2023

NCT04280718 Phase 2 ACTIVE NOT RECRUITING

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves)

Started: 9/18/2020

NCT05633407 Phase 2 COMPLETED

Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS

Started: 9/23/2022

NCT05810961 Phase 2 TERMINATED

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Primary Membranous Nephropathy (ZL-1103-014)

Started: 2/20/2023

NCT02965573 Phase 2 COMPLETED

A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness

Started: 12/30/2016

NCT04281472 Phase 2 COMPLETED

A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves)

Started: 4/15/2020

NCT03102593 Phase 2 COMPLETED

A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With ITP

Started: 3/13/2017

NCT03334058 Phase 2 COMPLETED

A Study to Evaluate the Safety, PD, PK and Efficacy of ARGX-113 in Patients With Pemphigus

Started: 10/18/2017

NCT07638566 Phase 2 NOT YET RECRUITING

A Study to Assess the Correct Dose, Safety and Efficacy of Empasiprubart in Adolescent Participants Aged 12 to Less Than 18 Years With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Started: 9/1/2026

NCT06436742 Phase 1 RECRUITING

A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)

Started: 9/24/2024

NCT07377396 Phase 1 RECRUITING

A Study to Assess the Safety of ARGX-124 in Healthy Volunteers

Started: 1/26/2026

NCT07612020 Phase 1 RECRUITING

A Study to Assess the Absolute Bioavailability of Empasiprubart SC Administered With an Autoinjector and the Pharmacokinetic Noninferiority of Empasiprubart SC Versus Intravenous (IV) in Healthy Adult Participants

Started: 3/16/2026

NCT06968338 Phase 1 COMPLETED

A Study to Assess the Safety of ARGX-213 in Healthy Volunteers

Started: 4/11/2025

NCT06799416 Phase 1 COMPLETED

A Study to Assess the Safety of ARGX-109 in Healthy Volunteers

Started: 1/14/2025

NCT05670704 Phase 1 COMPLETED

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Started: 2/21/2023

NCT05927415 Phase 1 COMPLETED

A Study to Test How Kidney Problems Influence the Blood Concentrations of Efgartigimod

Started: 7/17/2023

NCT03457649 Phase 1 COMPLETED

IV Dose Study to Assess the Safety, Tolerability, PK, PD and Immunogenicity of ARGX-113 in Healthy Volunteers

Started: 9/9/2015

NCT05817435 Phase 1 COMPLETED

A Phase 1 Bioequivalence Study of Efgartigimod PH20 SC Administered Via a Prefilled Syringe Versus a Vial+Syringe Presentation in Healthy Adults

Started: 3/13/2023

NCT04532125 Phase 1 COMPLETED

SAD and MAD Study With IV and SC Doses of ARGX-117

Started: 8/3/2020

NCT05163834 Phase 1 COMPLETED

Immune Response to PNEUMOVAX 23 in Healthy Adults Receiving Efgartigimod IV

Started: 11/17/2021

NCT04564066 Phase 1 COMPLETED

A Phase 1 Study to Compare the Safety and Effect of Efgartigimod as an Intravenous Infusion With the Effect of Efgartigimod as a Subcutaneous Injection in Healthy Volunteers

Started: 8/18/2020

NCT03334084 Phase 1 COMPLETED

A Study to Compare the PK, PD and Safety and Tolerability of a SC With an IV Formulation of ARGX-113 in Healthy Male Subjects

Started: 10/11/2017

NCT04073589 Phase 1 COMPLETED

Efgartigimod Co-administered Subcutaneously With rHuPH20 in Healthy Subjects

Started: 7/17/2019

NCT02759250 Phase 1 COMPLETED

A Study of ARGX-110 in Patients With Nasopharyngeal Carcinoma (NPC)

Started: 2/1/2015

NCT02055066 Phase 1 COMPLETED

A Phase 1b Study of ARGX-111 in Patients With Advanced Cancer.

Started: 1/1/2014

NCT07610564 Phase 1 NOT YET RECRUITING

A Study to Assess the Effect of Empasiprubart on Nerve Morphology by Ultrasound in Adults With Multifocal Motor Neuropathy

Started: 6/30/2026

NCT06909214 Phase 4 RECRUITING

A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)

Started: 4/17/2025

NCT06637072 Phase 4 COMPLETED

A Study to Assess Adults With CIDP Transitioning From IVIg to Efgartigimod PH20 SC

Started: 12/10/2024

Drug Candidates

Efgartigimod PH20 (ARGX-113) SC empasiprubart ARGX-117 Empasiprubart IV Efgartigimod PH20 SC Efgartigimod IV Efgartigimod IV or Efgartigimod PH20 SC ARGX-213 ARGX-119 ARGX-119 IV
Activity Status: Active
Last Trial Started: 9/1/2026
Last Trial Ended: 3/20/2026
Trials (12 months): 12
Completed Trials: 33
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.