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Clinical-Stage Companies / Hutchison Medipharma Limited

Hutchison Medipharma Limited

Pre-Approval PRO BETA
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Stale Activity

No new clinical trials started in 2+ years. Activity may be declining or company may be focusing on existing programs. Last trial started: 9/27/2022

57
Total Trials
11
Phase 3
14
Phase 2
1
Recruiting
382
Score

Pipeline by Phase

Phase 3
11
Phase 2
14
Phase 1
35

Therapeutic Focus

Healthy Gastric Cancer Non-small Cell Lung Cancer Neuroendocrine Tumors Ulcerative Colitis

Clinical Trials (57)

NCT03223376 Phase 3 COMPLETED

A Phase III Study of Fruquintinib in Combination With Paclitaxel in Second Line Gastric Cancer(FRUTIGA)

Started: 10/18/2017

NCT05009836 Phase 3 ACTIVE NOT RECRUITING

Clinical Study on Savolitinib + Osimertinib in Treatment of EGFRm+/MET+ Locally Advanced or Metastatic NSCLC

Started: 9/6/2021

NCT05015608 Phase 3 COMPLETED

Study on Savolitinib Combined With Osimertinib in Treatment of Advanced NSCLC With MET Amplification

Started: 11/22/2021

NCT04322539 Phase 3 COMPLETED

A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer

Started: 8/12/2020

NCT04923945 Phase 3 COMPLETED

Savolitinib for Treating Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Patients

Started: 8/19/2021

NCT02588170 Phase 3 COMPLETED

Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors

Started: 12/7/2015

NCT02589821 Phase 3 COMPLETED

Phase III Study of Surufatinib in Treating Advanced Pancreatic Neuroendocrine Tumors

Started: 12/7/2015

NCT02314819 Phase 3 COMPLETED

A Phase III Trial Evaluating Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients (FRESCO)

Started: 12/1/2014

NCT01882764 Phase 3 TERMINATED

HMPL-004 Maintenance Treatment in Subjects With Mild to Moderate Ulcerative Colitis

Started: 6/1/2013

NCT01805791 Phase 3 TERMINATED

A Phase III Trial of HMPL-004 in Patients With Mild to Moderate Active Ulcerative Colitis

Started: 3/1/2013

NCT02691299 Phase 3 COMPLETED

A Phase III Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer

Started: 12/9/2015

NCT04923932 Phase 2 COMPLETED

Savolitinib for Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients

Started: 7/27/2021

NCT05509699 Phase 2 COMPLETED

Surufatinib Plus Anti-PD-1/L1 as Maintenance Therapy in Extensive-Stage Small Cell Lung Cancer

Started: 9/27/2022

NCT04849351 Phase 2 COMPLETED

Clinical Study of HMPL-689 for Relapsed/Refractory Marginal Zone Lymphoma and Follicular Lymphoma

Started: 4/15/2021

NCT04169672 Phase 2 COMPLETED

Study of Surufatinib Single Agent or Surufatinib Combined With Toripalimab in Patients With Advanced Solid Tumors

Started: 12/26/2019

NCT00659802 Phase 2 COMPLETED

Phase II Study of HMPL-004 in Patients With Ulcerative Colitis

Started: 2/7/2008

NCT02196688 Phase 2 COMPLETED

Study of Fruquintinib in Patients With Metastatic Colorectal Cancer

Started: 4/1/2014

NCT02590965 Phase 2 COMPLETED

A Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer

Started: 5/29/2014

NCT02614495 Phase 2 COMPLETED

Study of Sulfatinib in Treating Advanced Medullary Thyroid Carcinoma and Iodine-refractory Differentiated Thyroid Carcinoma

Started: 2/24/2016

NCT03684967 Phase 2 WITHDRAWN

Study of Fruquintinib (HMPL-013) in High Risk Patients With Advanced NSCLC

Started: 5/8/2018

NCT02976116 Phase 2 COMPLETED

A Phase II Study of Fruquintinib in Combination With Gefitinib in Patients With Advanced Non-small Cell Lung Cancer

Started: 12/1/2016

NCT02966821 Phase 2 COMPLETED

Study of Surufatinib as Second-line Treatment in Patients With Biliary Tract Carcinoma

Started: 1/3/2017

NCT03251378 Phase 1 COMPLETED

A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers

Started: 12/11/2017

NCT02857998 Phase 1 COMPLETED

A Study of Hutchison MediPharma Limited(HMPL)-523 in Patients With Relapsed or Refractory Mature B-cell Neoplasms

Started: 12/27/2016

NCT03951623 Phase 1 COMPLETED

The Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Immune Thrombocytopenia Patients

Started: 8/12/2019

NCT03128164 Phase 1 COMPLETED

A Study of HMPL-689 in Patients With Lymphomas Failed of Standard of Care or no Standard of Care Existed

Started: 8/8/2017

NCT04755088 Phase 1 COMPLETED

Surufatinib Renal Impairment Study

Started: 2/12/2021

NCT04755075 Phase 1 COMPLETED

Surufatinib Hepatic Impairment Study

Started: 2/12/2021

NCT04510649 Phase 1 COMPLETED

Surufatinib DDI With a PPI and a CYP3A Inducer

Started: 7/9/2020

NCT04557397 Phase 1 COMPLETED

Fruquintinib CYP3A Inhibitor and Inducer Study

Started: 9/2/2020

NCT04645940 Phase 1 COMPLETED

Fruquintinib Food Effect and Proton Pump Inhibitor Study

Started: 9/24/2020

NCT04372394 Phase 1 COMPLETED

A Study to Assess the Effect of a High Fat Meal on Surufatinib in Healthy Subjects

Started: 8/14/2020

NCT04372407 Phase 1 COMPLETED

A Study to Assess the Effect of a Strong CYP3A Inhibitor, on Surufatinib in Healthy Subjects

Started: 7/9/2020

NCT02133157 Phase 1 COMPLETED

Phase I Study of Sulfatinib(HMPL-012) in Patients With Advanced Solid Tumors

Started: 4/1/2010

NCT02320409 Phase 1 COMPLETED

A Food Effect Phase I Study of the Sulfatinib in Healthy Subjects (HMPL-012)

Started: 12/1/2014

NCT02374645 Phase 1 COMPLETED

A Phase I Study of Safety and Pharmacokinetics of Volitinib in Combination With Gefitinib in EGFR(+) NSCLC

Started: 4/1/2015

NCT01645215 Phase 1 COMPLETED

Phase I Study of Fruquintinib(HMPL-013) in Patients With Advanced Solid Tumors

Started: 1/1/2011

NCT02590952 Phase 1 COMPLETED

A Phase I Study of Epitinib(HMPL-813) in Patients With Advanced Solid Tumors

Started: 10/31/2011

NCT01955304 Phase 1 COMPLETED

Food Effect Study of Single Dose of Fruquintinib (HMPL-013) in Healthy Subjects

Started: 6/1/2012

NCT02415023 Phase 1 COMPLETED

A Phase Ib/2 Clinical Study of Fruquintinib Combined With Paclitaxel in the Treatment of Advanced Gastric Cancer

Started: 11/9/2014

NCT01975077 Phase 1 COMPLETED

A Phase Ib Study of Fruquintinib in 3rd Line mCRC

Started: 12/1/2012

NCT02601248 Phase 1 COMPLETED

Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor

Started: 10/1/2012

NCT02689752 Phase 1 COMPLETED

A Mass Balance Study to Investigate the Absorption, Metabolism, and Excretion Of [14C] Fruquintinib

Started: 7/1/2016

NCT03483948 Phase 1 TERMINATED

Phase I Study of HMPL-523+Azacitidine in Elderly Patients With Acute Myeloid Leukemia

Started: 10/9/2018

NCT01985555 Phase 1 COMPLETED

Phase I Study of the Volitinib (HMPL-504) in Patients With Advanced Solid Tumors

Started: 5/1/2013

NCT03860948 Phase 1 COMPLETED

A Pharmacokinetic and Bioequivalence Study of Savolitinib Tablets in Healthy Chinese Male Volunteers

Started: 4/16/2019

NCT02017236 Phase 1 COMPLETED

A Food Effect Phase I Study of the Volitinib in Healthy Subjects

Started: 11/1/2013

NCT03860532 Phase 1 COMPLETED

Phase I Clinical Trial in Healthy Male Volunteers

Started: 9/1/2011

NCT02601274 Phase 1 TERMINATED

Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor

Started: 4/1/2015

NCT02966171 Phase 1 TERMINATED

A Dose Escalation Study to Assess the Safety and Tolerability of HMPL-453 in Patients With Advanced Solid Malignancies

Started: 1/1/2017

NCT02267967 Phase 1 COMPLETED

Phase Ib/II Study of Sulfatinib in Treating Advanced Neuroendocrine Tumors

Started: 10/31/2014

NCT03483259 Phase 1 COMPLETED

To Explore the Pharmacokinetics and Relative Bioavailability of Sulfatinib Capsules in Two Different Manufacturers

Started: 4/2/2018

NCT02631642 Phase 1 COMPLETED

A Study of HMPL-689 in Healthy Volunteers

Started: 3/23/2016

NCT01773018 Phase 1 COMPLETED

Phase I Study of the Volitinib (HMPL-504) in Patients With Advanced Solid Tumors

Started: 2/1/2012

NCT02105129 Phase 1 COMPLETED

A Study of the Safety, Tolerability and Pharmacokinetics of HMPL-523

Started: 5/1/2014

NCT02252913 Phase 1 COMPLETED

A Study of Safety and Pharmacokinetics of Volitinib With Docetaxel in Patients With Advanced Gastric Cancer

Started: 9/1/2014

NCT05173142 Phase 1 COMPLETED

A Phase Ib/II Clinical Study Evaluating HMPL-453 Tartrate as Monotherapy and in Combination With Chemotherapy or Toripalimab in Advanced Solid Tumors

Started: 1/22/2022

Drug Candidates

Savolitinib Surufatinib Anti-PD-1/L1 Savolitinib + Osimertinib HMPL-689 HMPL-523 fruquintinib with food/fruquintinib without food/fruquintinib with rabeprazole fruquintinib without food/fruquintinib with food/fruquintinib with rabeprazole surufatinib HMPL-004 low dose
Activity Status: Stale
Last Trial Started: 9/27/2022
Last Trial Ended: 4/21/2026
Trials (12 months): 0
Completed Trials: 50
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.