TheraRadar

LEO Pharma

Pre-Approval PRO BETA
174
Total Trials
45
Phase 3
53
Phase 2
3
Recruiting
1331
Score

Pipeline by Phase

Phase 3
45
Phase 2
53
Phase 1
74

Therapeutic Focus

Psoriasis Vulgaris Atopic Dermatitis Actinic Keratosis Healthy Chronic Hand Eczema

Clinical Trials (174)

NCT06311682 Phase 3 RECRUITING

A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis

Started: 6/10/2024

NCT07335588 Phase 3 RECRUITING

A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus

Started: 5/1/2026

NCT05355818 Phase 3 COMPLETED

Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema

Started: 7/14/2022

NCT05919082 Phase 3 COMPLETED

A Study to Investigate Efficacy and Safety With LEO 90100 Compared With Daivobet® Ointment in Adult Chinese Subjects With Stable Plaque Psoriasis

Started: 6/21/2023

NCT05295732 Phase 3 COMPLETED

The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI Ichthyosis

Started: 6/21/2022

NCT05958407 Phase 3 COMPLETED

A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy

Started: 8/28/2023

NCT06004050 Phase 3 COMPLETED

A Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Delgocitinib Cream in Chinese Adults and Adolescents With Moderate to Severe Chronic Hand Eczema

Started: 9/5/2023

NCT05259722 Phase 3 COMPLETED

A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema

Started: 6/15/2022

NCT04872101 Phase 3 COMPLETED

Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema (DELTA 2)

Started: 5/25/2021

NCT04871711 Phase 3 COMPLETED

Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema

Started: 5/10/2021

NCT04949841 Phase 3 COMPLETED

Open-label Multi-site Extension Trial in Subjects Who Completed the DELTA 1 or DELTA 2 Trials

Started: 8/23/2021

NCT04305327 Phase 3 TERMINATED

Efficacy and Safety of Brodalumab in Adolescents From 12 to 17 Years of Age With Moderate-to-severe Plaque Psoriasis

Started: 12/7/2022

NCT02549352 Phase 3 COMPLETED

Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up

Started: 11/1/2015

NCT01422434 Phase 3 COMPLETED

LEO 90105 Ointment in Japanese Subjects With Psoriasis

Started: 7/1/2011

NCT01195831 Phase 3 COMPLETED

Efficacy and Safety of Xamiol® Gel Compared to Calcipotriol Scalp Solution in Patients With Scalp Psoriasis

Started: 9/1/2010

NCT03587805 Phase 3 COMPLETED

Long-term Extension Trial in Subjects With Atopic Dermatitis Who Participated in Previous Tralokinumab Trials - ECZTEND

Started: 3/18/2018

NCT03115476 Phase 3 TERMINATED

A Trial to Compare the Incidence of Squamous Cell Carcinoma (SCC) and Other Skin Neoplasia on Skin Areas Treated With Ingenol Disoxate Gel or Vehicle Gel for Actinic Keratosis on Face and Chest or Scalp

Started: 6/16/2017

NCT03761537 Phase 3 COMPLETED

Tralokinumab in Combination With Topical Corticosteroids in Subjects With Severe Atopic Dermatitis - ECZTRA 7

Started: 12/13/2018

NCT04587453 Phase 3 COMPLETED

Tralokinumab in Combination With Topical Corticosteroids in Japanese Subjects With Moderate-to-severe Atopic Dermatitis

Started: 10/27/2020

NCT03131648 Phase 3 COMPLETED

Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 1 (ECZema TRAlokinumab Trial no. 1)

Started: 5/30/2017

NCT03160885 Phase 3 COMPLETED

Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 2 (ECZema TRAlokinumab Trial no. 2)

Started: 6/12/2017

NCT05194540 Phase 3 COMPLETED

Efficacy and Safety of Tralokinumab Administered by an Autoinjector in Adults and Adolescents With Moderate to Severe Atopic Dermatitis (INJECZTRA)

Started: 1/13/2022

NCT03526861 Phase 3 COMPLETED

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

Started: 6/19/2018

NCT03363854 Phase 3 COMPLETED

Tralokinumab in Combination With Topical Corticosteroids for Moderate to Severe Atopic Dermatitis - ECZTRA 3

Started: 2/22/2018

NCT01541553 Phase 3 COMPLETED

A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp

Started: 3/1/2012

NCT03806790 Phase 3 COMPLETED

Efficacy and Safety of LEO 90100 Foam in Japanese Subjects With Psoriasis Vulgaris

Started: 1/24/2019

NCT01600014 Phase 3 COMPLETED

Ingenol Mebutate Gel, 0.015% Repeat Use for Multiple Actinic Keratoses on Face and Scalp

Started: 5/1/2012

NCT01188928 Phase 3 COMPLETED

LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)

Started: 9/1/2010

NCT02549339 Phase 3 COMPLETED

Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-up

Started: 11/13/2015

NCT02361216 Phase 3 COMPLETED

Efficacy and Safety of Ingenol Mebutate Gel for Actinic Keratosis Applied on Large Area on Face, Scalp or Chest

Started: 4/1/2015

NCT01866163 Phase 3 COMPLETED

LEO 90100 Compared to Vehicle in Subjects With Psoriasis Vulgaris

Started: 6/1/2013

NCT00670241 Phase 3 COMPLETED

Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel Compared With Tacalcitol Ointment and the Gel Vehicle Alone in Patients With Psoriasis Vulgaris

Started: 4/1/2008

NCT02547363 Phase 3 COMPLETED

Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up

Started: 11/1/2015

NCT02668692 Phase 3 COMPLETED

LEO 80185 Gel (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Japanese Subjects With Psoriasis

Started: 2/1/2016

NCT02310646 Phase 3 COMPLETED

Patient Insights Following Use of LEO 90100 Aerosol Foam and Daivobet® Gel in Subjects With Psoriasis Vulgaris

Started: 1/1/2015

NCT02547233 Phase 3 COMPLETED

Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up

Started: 11/1/2015

NCT00691002 Phase 3 COMPLETED

Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment in Psoriasis Vulgaris on the Face and Skin Folds

Started: 5/1/2008

NCT02132936 Phase 3 COMPLETED

LEO 90100 Aerosol Foam Compared to Calcipotriol Plus Betamethasone Dipropionate Gel in Subjects With Psoriasis Vulgaris

Started: 6/1/2014

NCT00640822 Phase 3 COMPLETED

Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment Compared With Tacalcitol Ointment in Patients With Psoriasis on the Face and Skin Folds

Started: 2/1/2008

NCT01007591 Phase 3 COMPLETED

A Study Comparing LEO 80190 Ointment With Hydrocortisone Ointment, Both Applied Once Daily in the Treatment of Psoriasis Vulgaris on the Face and Intertriginous Areas

Started: 10/1/2009

NCT03395132 Phase 3 TERMINATED

Efficacy and Safety of Fucicort® Lipid Cream Compared to Combination Treatment With Fucidin® Cream Followed by Betamethasone (Lianbang Beisong®) Cream and Fucicort® Lipid Cream Vehicle in Clinically Infected Atopic Dermatitis/Eczema

Started: 7/31/2018

NCT01787383 Phase 3 COMPLETED

A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen With Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas With Actinic Keratosis on Face/Scalp and Trunk/Extremities

Started: 2/1/2013

NCT01130025 Phase 3 COMPLETED

Long-Term Innohep® Treatment Versus a Vitamin K Antagonist (Warfarin) for the Treatment of Venous Thromboembolism (VTE) in Cancer

Started: 8/1/2010

NCT01555463 Phase 3 COMPLETED

Safety and Efficacy of Azelaic Acid Foam, 15 % in Papulopustular Rosacea

Started: 9/1/2012

NCT02899962 Phase 3 COMPLETED

LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis Vulgaris

Started: 2/15/2017

NCT07013201 Phase 2 RECRUITING

A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis

Started: 9/11/2025

NCT02664805 Phase 2 COMPLETED

Proof of Concept, Twice Daily Applications of LEO 124249 Ointment in the Treatment of Chronic Hand Eczema

Started: 2/1/2016

NCT05923099 Phase 2 COMPLETED

A Trial to Evaluate the Efficacy and Safety of Different Doses of LEO 138559 in Adults With Moderate-to-severe Atopic Dermatitis

Started: 9/20/2023

NCT05388760 Phase 2 COMPLETED

Tralokinumab Monotherapy for Children With Moderate-to-severe Atopic Dermatitis - TRAPEDS 1 (TRAlokinumab PEDiatric Trial no. 1)

Started: 9/7/2022

NCT04922021 Phase 2 COMPLETED

An Evaluation of LEO 138559 in Adults With Moderate to Severe Atopic Dermatitis.

Started: 7/14/2021

NCT00758862 Phase 2 COMPLETED

The Pharmacokinetics of 2% TD1414 Cream in Adults With Secondarily Infected Traumatic Lesions (SITL) or Impetigo

Started: 12/1/2008

NCT00845481 Phase 2 COMPLETED

A Plaque Test Comparing the Anti-psoriatic Effect of Marketed Products for Topical Use for Psoriasis Vulgaris

Started: 1/1/2009

NCT00875277 Phase 2 COMPLETED

A Psoriasis Plaque Test With LEO 29102 Cream and Its Combination Products

Started: 4/1/2009

NCT00626795 Phase 2 COMPLETED

Efficacy, Safety, and Tolerability of TD1414 2% Cream in Impetigo and Secondarily Infected Traumatic Lesions (SITL)

Started: 2/1/2008

NCT03725722 Phase 2 COMPLETED

Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over an 8-week Treatment Period in Adult Subjects With Atopic Dermatitis.

Started: 12/28/2018

NCT00817219 Phase 2 COMPLETED

Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis Vulgaris

Started: 7/1/2009

NCT03683719 Phase 2 COMPLETED

Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema

Started: 11/28/2018

NCT01120223 Phase 2 COMPLETED

Safety and Efficacy of LEO 80185 Gel in Adolescent Subjects (Aged 12 to 17) With Scalp Psoriasis

Started: 5/1/2010

NCT01083758 Phase 2 COMPLETED

Safety and Efficacy of LEO 80185 Topical Suspension in Adolescent Subjects (Aged 12 to 17) With Scalp Psoriasis

Started: 4/1/2010

NCT03562377 Phase 2 COMPLETED

Vaccine Responses in Tralokinumab-Treated Atopic Dermatitis - ECZTRA 5 (ECZema TRAlokinumab Trial No. 5)

Started: 7/13/2018

NCT05470114 Phase 2 COMPLETED

A Multi-omics Disease Signature Trial in Adult Patients With Moderate to Severe AD

Started: 5/19/2022

NCT01963793 Phase 2 COMPLETED

Topical Aprepitant in Prurigo Patients

Started: 10/1/2013

NCT02387853 Phase 2 COMPLETED

Safety and Efficacy of Once Daily Topical Treatment With LEO 90100 Aerosol Foam in Adolescent Subjects With Plaque Psoriasis

Started: 3/1/2016

NCT01607853 Phase 2 COMPLETED

A Short-contact Plaque Test Study With Daivobet® Gel in Psoriasis Vulgaris

Started: 6/1/2012

NCT02038569 Phase 2 COMPLETED

An International, Multi-centre, Prospective, Non-controlled, Open, Single-group, 8-week Trial in Adolescent Subjects

Started: 1/1/2014

NCT01461655 Phase 2 COMPLETED

Efficacy and the Tolerability of the Sequential Application of Two Marketed Products in Patients With Acne Vulgaris

Started: 11/1/2011

NCT01998984 Phase 2 COMPLETED

Efficacy and Safety of Ingenol Mebutate Gel 0.06% When Applied Once Daily for 2, 3 or 4 Consecutive Days to a Treatment Area of Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis

Started: 1/1/2014

NCT02518048 Phase 2 COMPLETED

A Psoriasis Plaque Test Trial With LEO 90100 Compared to Betesil® in Patients With Psoriasis Vulgaris

Started: 8/1/2015

NCT01037881 Phase 2 COMPLETED

LEO 29102 Cream in the Treatment of Atopic Dermatitis

Started: 12/1/2009

NCT02305888 Phase 2 COMPLETED

Safety of LEO 43204 for Actinic Keratosis Applied on Face/Chest, Scalp and Trunk/Extremities, Respectively

Started: 3/1/2015

NCT01347255 Phase 2 COMPLETED

A Psoriasis Plaque Test Study With LEO 90100 Cutaneous Spray, Ointment, in Psoriasis Vulgaris

Started: 5/1/2011

NCT00704262 Phase 2 COMPLETED

Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin Folds

Started: 5/1/2008

NCT00764751 Phase 2 COMPLETED

Efficacy and Safety of LEO 19123 Cream in the Treatment of Psoriasis Vulgaris

Started: 9/1/2008

NCT01116895 Phase 2 COMPLETED

A Proof of Concept Study Comparing Three Doses of an Oral Solution of LEO 22811 With a Placebo Oral Solution for the Treatment of Psoriasis Vulgaris

Started: 5/1/2010

NCT01536886 Phase 2 COMPLETED

LEO 90100 Compared With Calcipotriol Plus Betamethasone Dipropionate Ointment, LEO 90100 Vehicle and Ointment Vehicle in Subjects With Psoriasis Vulgaris

Started: 5/1/2012

NCT01536938 Phase 2 COMPLETED

LEO 90100 in the Treatment of Psoriasis Vulgaris

Started: 5/1/2012

NCT01600222 Phase 2 COMPLETED

Effect of LEO 90100 on the HPA Axis and Calcium Metabolism in Subjects With Extensive Psoriasis VulgarisExtensive Psoriasis Vulgaris

Started: 5/1/2012

NCT05332366 Phase 2 COMPLETED

A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing Alopecia

Started: 4/19/2022

NCT02575950 Phase 2 COMPLETED

Explorative Trial Evaluating the Efficacy and Tolerability of LEO43204 in Moderate to Severe Acne

Started: 6/1/2016

NCT03958955 Phase 2 TERMINATED

Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.

Started: 7/9/2019

NCT02561585 Phase 2 COMPLETED

LEO 124249 Ointment in the Treatment of Alopecia Areata

Started: 1/1/2016

NCT01722812 Phase 2 COMPLETED

Cromoglicate in Psoriasis

Started: 11/1/2012

NCT01701843 Phase 2 TERMINATED

Cromoglicate in Mastocytosis

Started: 10/1/2012

NCT02695940 Phase 2 COMPLETED

Trial Twice Daily Application of LEO 124249 Ointment 30 mg/g in Treatment of Mild to Moderate Inverse Psoriasis

Started: 3/1/2016

NCT03325296 Phase 2 TERMINATED

Efficacy of Twice Daily Application of LEO 124249 Ointment 30 mg/g for 12 Weeks on Eyebrow Alopecia Areata.

Started: 10/30/2017

NCT02377999 Phase 2 COMPLETED

Safety and Efficacy of Repeat Use of Picato® 0.05% in the Treatment of Anogenital Warts

Started: 2/1/2015

NCT02416258 Phase 2 COMPLETED

A Psoriasis Plaque Test Trial With LP0113 Spray in Patients With Psoriasis Vulgaris (LP0113-1123)

Started: 4/1/2015

NCT01229098 Phase 2 COMPLETED

Effect of LEO 80185 Gel on the HPA Axis and Calcium Metabolism in Subjects With Extensive Psoriasis Vulgaris

Started: 10/1/2010

NCT04154293 Phase 2 COMPLETED

A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis

Started: 12/3/2019

NCT00617903 Phase 2 COMPLETED

Exploration of Safety and Efficacy of AzA 15% Foam Twice a Day in Rosacea

Started: 1/1/2008

NCT01025635 Phase 2 COMPLETED

Safety and Efficacy of Azelaic Acid Foam, 15% in Papulopustular Rosacea

Started: 12/1/2009

NCT02888236 Phase 2 COMPLETED

LEO 32731 for the Treatment of Moderate to Severe Psoriasis Vulgaris

Started: 9/1/2016

NCT06444867 Phase 1 COMPLETED

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

Started: 1/7/2025

NCT03995550 Phase 1 WITHDRAWN

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single and Multiple Doses of LEO 142397 in Healthy People, Including Japanese

Started: 7/3/2019

NCT04883333 Phase 1 COMPLETED

A Single and Multiple Ascending-dose Trial of LEO 153339 in Healthy Adults

Started: 5/17/2021

NCT04807751 Phase 1 COMPLETED

Clinical Trial to Evaluate UV-light-induced Allergic Skin Reactions After Application of Delgocitinib Cream

Started: 3/25/2021

NCT03673527 Phase 1 COMPLETED

Tacrolimus Blood Levels After Topical Application of Tacrolimus on Healthy Skin

Started: 11/22/2018

NCT05682352 Phase 1 COMPLETED

Investigating the Safety of LEO 158968 in Healthy Volunteers

Started: 2/7/2023

NCT04361136 Phase 1 COMPLETED

Clinical Trial to Evaluate Light-induced Skin Reactions After Application of Delgocitinib Cream

Started: 4/23/2020

NCT04674826 Phase 1 COMPLETED

A Trial to Compare the Pharmacokinetics of Tralokinumab in Healthy Subjects

Started: 2/8/2021

NCT05486117 Phase 1 COMPLETED

Pharmacokinetics of Delgocitinib 20 mg/g Cream in Subjects With Chronic Hand Eczema

Started: 9/6/2022

NCT01820260 Phase 1 COMPLETED

Safety and Efficacy of Ingenol Mebutate Once Daily for 2 or 3 Consecutive Days in Subjects With Actinic Keratosis

Started: 4/1/2013

NCT01580488 Phase 1 COMPLETED

A Plaque Test Study With LEO 35299 in Psoriasis Vulgaris

Started: 4/1/2012

NCT01768013 Phase 1 COMPLETED

The Pharmacokinetics of LEO 90105 (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Japanese Subjects With Extensive Psoriasis Vulgaris

Started: 7/1/2012

NCT01449513 Phase 1 COMPLETED

PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal Microscopy

Started: 9/1/2011

NCT01922050 Phase 1 COMPLETED

A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic Keratosis

Started: 10/1/2013

NCT02100813 Phase 1 COMPLETED

Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis

Started: 5/1/2014

NCT02120456 Phase 1 COMPLETED

Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis

Started: 5/1/2014

NCT01211964 Phase 1 COMPLETED

LEO 22811 - Single Dose Bioavailability Study of Tablet Versus Oral Solution in Healthy Subjects

Started: 9/1/2010

NCT02376049 Phase 1 COMPLETED

A Clinical Trial to Compare Topical Agents in Adults With Mild to Moderate Atopic Dermatitis (AD)

Started: 2/1/2015

NCT02605057 Phase 1 COMPLETED

Dermatopharmacokinetic Trial of LEO 80185 Gel

Started: 11/1/2015

NCT02600598 Phase 1 COMPLETED

Biological Effects of LEO 43204 in Actinic Keratosis

Started: 7/1/2016

NCT02219633 Phase 1 COMPLETED

Effect of LEO 39652 Cream in Adults With Mild to Moderate Atopic Dermatitis (AD)

Started: 7/1/2014

NCT00891709 Phase 1 COMPLETED

LEO 29102 Single and Multiple Dose Study by Dermal Application

Started: 3/1/2009

NCT03514511 Phase 1 COMPLETED

Safety and Tolerability of LEO 138559 in Healthy Subjects and Subjects With Atopic Dermatitis

Started: 5/7/2018

NCT01387711 Phase 1 COMPLETED

PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Histology

Started: 8/1/2011

NCT02124239 Phase 1 COMPLETED

Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions

Started: 4/1/2014

NCT03898583 Phase 1 COMPLETED

Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamics Effect of Calcipotriol/Betamethasone Dipropionate in a New Administration Form in Subjects With Chronic Plaque Psoriasis.

Started: 4/15/2019

NCT01293383 Phase 1 COMPLETED

A Study Evaluating the Safety of LEO 90105 and Its Vehicle, After Multiple Administration on Intact Skin of Healthy Japanese Male Subjects

Started: 3/1/2011

NCT02379793 Phase 1 COMPLETED

Skin Irritation Test of LEO 80185 Gel in Healthy Japanese Subjects

Started: 3/1/2015

NCT01141179 Phase 1 COMPLETED

The Impact of Renal Impairment on the Pharmacokinetic and Pharmacodynamic of LEO 27847

Started: 5/1/2010

NCT01167309 Phase 1 COMPLETED

LEO 27847 - Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in Secondary Hyperparathyroidism Patients

Started: 6/1/2010

NCT01946386 Phase 1 COMPLETED

A Vasoconstriction Study With LEO 90100

Started: 9/1/2013

NCT01892137 Phase 1 COMPLETED

Histological Confirmation of Clinical Clearance of Actinic Keratoses Following Treatment With Ingenol Mebutate Gel, 0.05%

Started: 7/1/2013

NCT01803477 Phase 1 COMPLETED

Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic Keratosis on the Forearm

Started: 2/1/2013

NCT01423656 Phase 1 COMPLETED

Safety, Tolerability and Pharmacokinetic Study in Healthy Subjects by Dermal Application of a LEO 29102

Started: 8/1/2011

NCT01297166 Phase 1 COMPLETED

A Psoriasis Plaque Test on LEO 27989 Ointment and Calcipotriol Plus LEO 27989 Ointment in Patients With Psoriasis Vulgaris

Started: 2/1/2011

NCT01007383 Phase 1 COMPLETED

LEO 27847 - A Study in Healthy Male Subjects

Started: 9/1/2009

NCT01105286 Phase 1 COMPLETED

A Psoriasis Plaque Test Comparing Eight Different Formulations of Vitamin D Analogues for the Treatment of Psoriasis

Started: 4/1/2010

NCT01293357 Phase 1 COMPLETED

A Study Evaluating Skin Irritation, Phototoxicity and Safety After Administration of LEO 90105 on Intact Skin of Healthy Japanese Male Subjects

Started: 12/1/2010

NCT03442244 Phase 1 COMPLETED

Skin Irritation of LEO 90100 Foam (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Healthy Japanese Subjects

Started: 1/30/2018

NCT00833872 Phase 1 COMPLETED

LEO 22811 - A Phase 1, Double-Blind, Placebo-controlled, Single and Multiple Oral Dose Study in Healthy Subjects

Started: 1/1/2009

NCT02355639 Phase 1 COMPLETED

A Single-Centre Clinical Trial to Assess Steroid Induced Skin Atrophy on Healthy Skin

Started: 1/1/2015

NCT01850849 Phase 1 COMPLETED

Safety, Tolerability and Pharmacokinetics in AD Subjects and Healthy Subjects of Cutaneous Application of LEO 39652 Cream

Started: 5/1/2013

NCT01005823 Phase 1 COMPLETED

A Safety, Tolerability and Pharmacokinetic Study of LEO 29102 in Subjects With Atopic Dermatitis

Started: 10/1/2009

NCT02650505 Phase 1 COMPLETED

A Clinical Study to Evaluate the Sensitizing Potential of LEO 43204 Gel

Started: 2/1/2016

NCT01143298 Phase 1 COMPLETED

LEO 27847 - Single Dose Bioavailability Study of Oral Solution Versus Tablet in Healthy Subjects

Started: 6/1/2010

NCT03556592 Phase 1 COMPLETED

Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4

Started: 8/13/2018

NCT02103725 Phase 1 COMPLETED

A Multi-Centre Clinical Trial to Evaluate a Left-Right Design in Adults With Mild to Moderate Atopic Dermatitis

Started: 4/1/2014

NCT01837576 Phase 1 COMPLETED

An Exploratory Psoriasis Plaque Test Study With Different Dose Combinations of Calcipotriol Plus Betamethasone Dipropionate in the Daivobet® Gel Vehicle in Psoriasis Vulgaris

Started: 4/1/2013

NCT03476746 Phase 1 COMPLETED

Dermatopharmacokinetic Trial of LEO 90100 Foam

Started: 3/20/2018

NCT02424305 Phase 1 COMPLETED

Pharmacokinetics of LEO 43204 Gel in Actinic Keratosis Administered Under Maximal Use Conditions

Started: 5/1/2015

NCT01935869 Phase 1 COMPLETED

Combined Cumulative Irritation Potential and Repeat Insult Patch Test of LEO 90100

Started: 8/1/2013

NCT03826901 Phase 1 COMPLETED

Delgocitinib Cream for the Treatment of Moderate to Severe Atopic Dermatitis During 8 Weeks in Adults, Adolescents, and Children

Started: 2/20/2019

NCT01447758 Phase 1 TERMINATED

Safety, Tolerability and Pharmacokinetics of LEO 29102 Cream in Atopic Dermatitis.

Started: 9/1/2011

NCT01466478 Phase 1 COMPLETED

An Exploratory Psoriasis Plaque Test Study With LEO 29102 Plus Calcipotriol, Ointment, in Psoriasis Vulgaris

Started: 11/1/2011

NCT00958516 Phase 1 COMPLETED

Assessment of the Phototoxic Potential of LEO 29102 Cream

Started: 9/1/2009

NCT05099133 Phase 1 COMPLETED

A Trial to Evaluate Pharmacokinetics, Immunogenicity, Safety, and Tolerability of LEO 138559 in Healthy Japanese Subjects

Started: 11/3/2021

NCT01703078 Phase 1 COMPLETED

Safety and Tolerability of Different Concentrations of an Ingenol Derivative Field Therapy in the Treatment of Actinic Keratosis

Started: 11/1/2012

NCT02577185 Phase 1 COMPLETED

An Exploratory Trial Investigating the Neurogenic Component in Psoriasis Vulgaris by Use of Botulinum Toxin A

Started: 11/1/2015

NCT01105234 Phase 1 COMPLETED

An Irritation Study With New Calcipotriol Ointment Formulations in Healthy Subjects

Started: 4/1/2010

NCT02392130 Phase 1 COMPLETED

A Clinical Trial to Assess the Potential of LEO 130852A Gel to Reduce Steroid Induced Skin Atrophy on Healthy Skin

Started: 3/1/2015

NCT01043224 Phase 1 COMPLETED

A Psoriasis Plaque Test Comparing Products for the Treatment of Psoriasis Vulgaris

Started: 1/1/2010

NCT03669757 Phase 1 COMPLETED

Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamic Effect of Different Concentrations of a New Anti-inflammatory Substance in Subjects With Chronic Plaque Psoriasis

Started: 9/27/2018

NCT01257919 Phase 1 COMPLETED

Safety and Pharmacokinetics of Azelaic Acid Foam, 15% in Papulopustular Rosacea

Started: 1/1/2011

NCT03231124 Phase 1 COMPLETED

Multiple Dose Study With Incremental Dosing to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral Doses of LEO 32731 in Healthy Male Japanese Subjects.

Started: 7/25/2017

NCT01430312 Phase 1 COMPLETED

21 Day Irritancy Test of Azelaic Acid Pre-foam Formulation

Started: 9/1/2011

NCT01430533 Phase 1 COMPLETED

Human Repeated Insult Patch Test (HRIPT) of Azelaic Acid Pre Foam Formulation

Started: 9/1/2011

NCT03812198 Phase 1 COMPLETED

A Trial to Investigate the Safety, Tolerability, and Drug Levels in Blood After Single and Multiple Doses of LEO 32731 in Healthy People

Started: 1/22/2019

NCT03126578 Phase 1 COMPLETED

Open-label, Single Center, Non-randomized, Fixed Sequence Phase 1 Drug-drug Interaction Study With LEO 32731 and Midazolam

Started: 5/31/2017

NCT02973776 Phase 1 COMPLETED

Vasoconstriction Trial With LEO 90100 Aerosol Foam

Started: 12/1/2016

NCT02496546 Phase 1 COMPLETED

An Explorative Trial Evaluating the Effect of LEO 32731 Cream in Adults With Mild to Moderate Atopic Dermatitis (AD)

Started: 7/1/2015

NCT02514694 Phase 1 COMPLETED

LEO 32731 - A Phase I Study in Healthy Subjects

Started: 7/1/2015

NCT02753218 Phase 1 TERMINATED

A Phase I Study With LEO 32731 and Midazolam in Healthy Male Subjects

Started: 4/1/2016

NCT02126371 Phase 1 COMPLETED

LP0058-1005 - A Open-Label, Four-Way Crossover and Food-Effect Study of LEO 32731 in Healthy Subjects

Started: 5/1/2014

NCT01310049 Phase 1 COMPLETED

LEO 32731 - A Study in Healthy Male Subjects

Started: 3/1/2011

NCT04306315 Phase 4 COMPLETED

Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body Weight

Started: 7/21/2022

NCT04533737 Phase 4 TERMINATED

Efficacy and Safety of Brodalumab Compared With Guselkumab in the Treatment of Plaque Psoriasis After Inadequate Response to Ustekinumab

Started: 12/17/2020

NCT03331835 Phase 4 COMPLETED

A Trial Comparing the Efficacy of Subcutaneous Injections of Brodalumab to Oral Administrations of Fumaric Acid Esters in Adults With Moderate to Severe Plaque Psoriasis

Started: 11/3/2017

NCT01926496 Phase 4 COMPLETED

Risk of Squamous Cell Carcinoma on Skin Areas Treated With Ingenol Mebutate Gel, 0.015% and Imiquimod Cream, 5%

Started: 9/11/2013

NCT02406014 Phase 4 COMPLETED

Efficacy and Safety of Ingenol Mebutate Gel 0.015% Compared to Diclofenac Sodium Gel 3% in Subjects With Actinic Keratoses on the Face or Scalp

Started: 4/1/2015

NCT02533973 Phase 4 COMPLETED

Long-term Treatment of Scalp Psoriasis With Xamiol® Gel in a Large Adult Chinese Population

Started: 9/1/2015

NCT03710044 Phase 4 WITHDRAWN

Investigation of Flare and Remission in Subjects With Atopic Dermatitis

Started: 1/14/2019

NCT00855595 Phase 4 COMPLETED

Efficacy of Topical Azelaic Acid 15% Gel Plus Anti-inflammatory Dose Doxycycline or Metronidazole Gel 1% Plus Anti-inflammatory Dose Doxycycline in Moderate Papulopustular Rosacea

Started: 2/1/2009

Drug Candidates

LEO 158968 Delgocitinib Cream vehicle LEO 142397 LEO 124249 ointment LEO 124249 ointment vehicle LEO 153339 Delgocitinib cream Delgocitinib cream vehicle topical formulation of tacrolimus
Activity Status: Active
Last Trial Started: 5/1/2026
Last Trial Ended: 4/29/2026
Trials (12 months): 2
Completed Trials: 160
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.