Philogen
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (38)
Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients
Started: 9/20/2018
Neoadjuvant L19IL2/L19TNF- Pivotal Study
Started: 7/1/2016
L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)
Started: 6/1/2026
Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients
Started: 7/12/2024
A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence
Started: 5/22/2024
L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma
Started: 2/1/2026
L19IL2/TNF in Patients With Basal Cell Carcinoma
Started: 2/1/2026
A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or Oligodendroglioma
Started: 1/30/2026
Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma
Started: 8/28/2020
A Randomized, Placebo-controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of F8IL10 (Dekavil) in Patients With Active RA Receiving MTX
Started: 10/1/2014
F16IL2 Plus Paclitaxel in Metastatic Merkel Cell Carcinoma
Started: 10/25/2013
Intratumoral Application of L19IL2 in Patients With Malignant Melanoma
Started: 4/1/2010
Clinical Study Phase II of L19IL2 in Combination With Dacarbazine in Patients With Metastatic Melanoma
Started: 6/1/2008
131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors
Started: 10/1/2009
A Study to Evaluate the Safety and Preliminary Signs of Efficacy of [177Lu]Lu-OncoFAP-23 Alone or in Combination With L19-IL2 as a Treatment of Metastatic FAP-positive Solid Tumors
Started: 10/31/2025
A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis
Started: 1/1/2026
Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma
Started: 1/20/2021
A Phase I Study to Evaluate the Safety and Dosimetry of Imaging With 68Ga-OncoACP3 in Prostate Cancer
Started: 5/27/2026
A Phase I Study to Evaluate the Safety and Efficacy of L19IL2 in Combination With Ruxolitinib in Patients With Advanced Solid Tumors
Started: 5/1/2026
A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoCAIX in Patients With CAIX-positive Cancer
Started: 4/16/2025
A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoACP3 in Patients With Prostate Cancer
Started: 4/8/2025
Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment
Started: 3/31/2023
A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors
Started: 4/27/2023
Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression
Started: 6/1/2022
A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Started: 7/31/2013
A Study of the Tumor-targeting Human F16IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Very Low-dose Cytarabine in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation
Started: 4/13/2016
Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse
Started: 5/31/2019
Trial to Find and Investigate a Safe Dose of F16IL2 and BI 836858 in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation
Started: 12/2/2016
Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients
Started: 8/6/2008
Phase 1 Dose-finding Study of L19TNFα Plus Melphalan Using Isolated Inferior Limb Perfusion (ILP) in Subjects With Intransit Stage III/IV Melanoma
Started: 10/1/2008
L19TNFα in Combination With Doxorubicin in Patients With Advanced Solid Tumours
Started: 1/16/2013
Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients
Started: 9/1/2011
A Dose Finding and Efficacy Study of the Tumour Targeting Human 131I-F16SIP Monoclonal Antibody in Patients With Cancer
Started: 9/1/2008
Combination Therapy of F16IL2 and Doxorubicin in Solid Tumour Patients
Started: 6/1/2008
131I-L19SIP Radioimmunotherapy Combined With Radiochemotherapy in Patients With Locally-advanced Non Small Cell Lung Cancer (NSCLC)
Started: 5/1/2010
Radioimmunotherapy With 131I-L19SIP in Patients With Cancer
Started: 11/1/2008