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Clinical-Stage Companies / Sichuan Kelun-Biotech Biopharmaceutical

Sichuan Kelun-Biotech Biopharmaceutical

Pre-Approval PRO BETA
49
Total Trials
12
Phase 3
24
Phase 2
34
Recruiting
521
Score

Pipeline by Phase

Phase 3
12
Phase 2
24
Phase 1
18

Therapeutic Focus

Advanced Solid Tumors Non-Small Cell Lung Cancer Metastatic Colorectal Cancer Non-small Cell Lung Cancer Triple Negative Breast Cancer

Clinical Trials (49)

NCT06279364 Phase 3 RECRUITING

A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer

Started: 2/28/2024

NCT06670196 Phase 3 RECRUITING

A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Started: 11/27/2024

NCT07071337 Phase 3 RECRUITING

A Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With Unresectable Locally Advanced, Relapsed, or Metastatic HR+/HER2- Breast Cancer Who Have Previously Failed Endocrine Therapy

Started: 7/18/2025

NCT06081959 Phase 3 RECRUITING

Study of SKB264 for Locally Advanced, Recurrent or Metastatic HR+/HER2- Breast Cancer

Started: 10/31/2023

NCT06711900 Phase 3 RECRUITING

A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination With Pembrolizumab as First-Line Treatment for PD-L1 Negative Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Started: 10/30/2024

NCT03426371 Phase 3 TERMINATED

Epidermal Growth Factor Receptor (EGFR) Antagonist Chimeric Anti-EGFR Monoclonal Antibody Trial

Started: 3/18/2018

NCT06448312 Phase 3 ACTIVE NOT RECRUITING

A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Started: 6/7/2024

NCT06968585 Phase 3 ACTIVE NOT RECRUITING

A Study of A166 Versus Trastuzumab Emtansine (T-DM1) in Patients With HER2-Positive Unresectable or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane Therapy

Started: 7/18/2023

NCT04835142 Phase 3 COMPLETED

Comparison of A140 and Erbitux Combined With mfolfox6 to Evaluate Efficacy and Safety of First-line Treatment for Ras Wild-type mCRC

Started: 12/31/2020

NCT05870319 Phase 3 ACTIVE NOT RECRUITING

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

Started: 6/26/2023

NCT05294172 Phase 3 ACTIVE NOT RECRUITING

KL-A167 Injection Combined With Cisplatin and Gemcitabine vs Placebo Combined With Cisplatin and Gemcitabine in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma

Started: 6/7/2022

NCT05347134 Phase 3 ACTIVE NOT RECRUITING

SKB264 Injection vs Investigator Selected Regimens to Treat Locally Advanced, Recurrent or Metastatic Triple-negative Breast Cancer

Started: 6/10/2022

NCT05351788 Phase 2 RECRUITING

SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung Cancer.

Started: 5/20/2022

NCT07448922 Phase 2 RECRUITING

A Study of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced Gynecological Malignant Tumors

Started: 4/8/2026

NCT07230405 Phase 2 RECRUITING

A Phase II Study of SKB571 in Patients With Lung Cancer

Started: 1/19/2026

NCT07329322 Phase 2 RECRUITING

Phase II Study of Sacituzumab Tirumotecan in Combination With Osimertinib or Sacituzumab Tirumotecan for Neoadjuvant Treatment in Patients With Resectable Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Started: 3/30/2026

NCT07308106 Phase 2 RECRUITING

A Phase II Clinical Study of SKB571 as Monotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With MET Abnormalities

Started: 4/3/2026

NCT07296809 Phase 2 RECRUITING

SKB500 Combinations in Patients With Small Cell Lung Cancer

Started: 1/30/2026

NCT07019675 Phase 2 RECRUITING

A Study of SKB518 in Patients With Lung Cancer

Started: 8/29/2025

NCT07299825 Phase 2 RECRUITING

A Study of A166 in Patients With HER2-Positive Unresectable or Metastatic Breast Cancer

Started: 9/20/2024

NCT05496426 Phase 2 TERMINATED

A Study of KL130008 in Adults With Severe Alopecia Areata

Started: 11/9/2022

NCT07341100 Phase 2 ACTIVE NOT RECRUITING

Study to Evaluate the Preliminary Efficacy of SKB264 and the Effect of Clarithromycin on the PK of SKB264 in OC

Started: 1/16/2026

NCT07564466 Phase 2 NOT YET RECRUITING

A Study of SKB571 in Participants With Gastrointestinal Tumors

Started: 6/30/2026

NCT05631262 Phase 2 ACTIVE NOT RECRUITING

SKB264 Monotherapy in Selected Subjects With Advanced Solid Tumors

Started: 11/30/2022

NCT05445908 Phase 2 ACTIVE NOT RECRUITING

SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer

Started: 8/17/2022

NCT07324629 Phase 2 NOT YET RECRUITING

Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic Carcinoma

Started: 6/1/2026

NCT03848286 Phase 2 COMPLETED

KL-A167 Injection in Recurrent or Metastatic Nasopharyngeal Carcinoma

Started: 3/6/2019

NCT03580564 Phase 2 COMPLETED

An Open, Multicenter Phase II Study to Evaluate the Safety and Efficacy of KL-A167 Injection in Relapsed or Refractory Classical Hodgkin's Lymphoma

Started: 8/1/2018

NCT07609667 Phase 2 NOT YET RECRUITING

SKB315 in Combination Therapy in Patients With Advanced or Metastatic GC/ GEJ Adenocarcinoma

Started: 6/30/2026

NCT07622186 Phase 2 NOT YET RECRUITING

A Study of SKB571 Combination Therapy in Participants With Non-Small Cell Lung Cancer (NSCLC)

Started: 7/31/2026

NCT07668154 Phase 2 NOT YET RECRUITING

A Phase II Study to Evaluate the Efficacy and Safety of SKB571 in Recurrent or Metastatic HNSCC Participants

Started: 7/31/2026

NCT06826040 Phase 1 RECRUITING

SKB445 for Injection in Solid Tumors

Started: 2/5/2025

NCT07087197 Phase 1 RECRUITING

A Study of SKB107 in Advanced Solid Tumors With Bone Metastases

Started: 8/15/2025

NCT06428331 Phase 1 RECRUITING

A Study of SKB518 in Patients With Advanced Solid Tumors

Started: 7/4/2024

NCT06725381 Phase 1 RECRUITING

A Phase 1 Study of SKB571 in Subjects With Advanced Solid Tumors

Started: 12/17/2024

NCT07488065 Phase 1 RECRUITING

A Study of SKB575 (HBM7575) Injection in Healthy Participants and Atopic Dermatitis Participants

Started: 3/31/2026

NCT05367635 Phase 1 RECRUITING

A Study of SKB315 in Patients With Advanced Solid Tumors

Started: 3/16/2022

NCT07380386 Phase 1 RECRUITING

SKB105 for Injection in Advanced Solid Tumors

Started: 3/5/2026

NCT07459998 Phase 1 RECRUITING

SKB103 for Injection in Advanced Solid Tumors

Started: 4/23/2026

NCT06736327 Phase 1 RECRUITING

A Study on the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of SKB500 in Subjects With Advanced Solid Tumors

Started: 12/13/2024

NCT06726369 Phase 1 RECRUITING

A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of MK-6204 (SKB535) for Injection in Participants With Advanced Solid Tumors

Started: 12/12/2024

NCT05906537 Phase 1 ACTIVE NOT RECRUITING

SKB410 for Injection in Solid Tumors

Started: 7/6/2023

NCT03017807 Phase 1 COMPLETED

Safety and Pharmacokinetics of Recombinant Anti-EGFr Antibody in Patients With Metastatic Colorectal Cancer

Started: 12/30/2016

NCT07545265 Phase 1 NOT YET RECRUITING

SKB565 for Injection in Advanced Solid Tumors

Started: 6/1/2026

NCT05549804 Phase 1 COMPLETED

A Study of Intratumoral KL340399 in Patients With Advanced Solid Tumors

Started: 8/30/2022

NCT05387928 Phase 1 COMPLETED

A Study of KL340399 in Patients With Advanced Solid Tumors

Started: 6/7/2022

NCT05265091 Phase 1 ACTIVE NOT RECRUITING

A Study of KL590586 in Patients With Advanced Solid Tumors

Started: 9/15/2021

NCT05311397 Phase 1 ACTIVE NOT RECRUITING

A Study of A166 in Patients With Advanced Solid Malignant Tumors

Started: 8/9/2018

NCT07586943 Phase 1 NOT YET RECRUITING

SKB118 Injection in Advanced Solid Tumors

Started: 6/1/2026

Drug Candidates

SKB410 for injection Recombinant Anti-EGFr Antibody SKB264 KL-A167 KL-140 KL130008/Placebo SKB518 for injection SKB571 for injection Sacituzumab Tirumotecan SKB445 for injection
Activity Status: Active
Last Trial Started: 7/31/2026
Last Trial Ended: 4/21/2025
Trials (12 months): 19
Completed Trials: 6
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.