United
Pre-Approval PRO BETAAlso known as: United Therapeutics, United BioPharma, United Pharmaceuticals
Pipeline by Phase
Therapeutic Focus
Clinical Trials (73)
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
Started: 10/30/2023
Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis
Started: 6/1/2021
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease
Started: 9/6/2022
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
Started: 1/24/2019
Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)
Started: 12/21/2018
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Started: 9/23/2019
Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis
Started: 10/4/2022
A Pharmacokinetic Substudy of the TDE-PH-304 Protocol
Started: 8/1/2013
A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)
Started: 5/8/2018
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH
Started: 1/20/2021
An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension
Started: 9/11/2013
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
Started: 8/15/2017
Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF
Started: 1/30/2018
Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy
Started: 6/26/2012
Study to Compare Triple Therapy (Oral Treprostinil, Ambrisentan, and Tadalafil) With Dual Therapy (Ambrisentan, Tadalafil, and Placebo) in Subjects With Pulmonary Arterial Hypertension
Started: 10/1/2017
Study to Evaluate Efficacy and Safety of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Sickle Cell Disease (SCD)
Started: 6/1/2017
FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)
Started: 12/1/2008
Efficacy and Safety of Oral UT-15C Tablets to Treat Pulmonary Arterial Hypertension
Started: 6/1/2009
Safety and Efficacy of Inhaled Treprostinil in Patients With PAH
Started: 6/1/2012
To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults
Started: 4/1/2025
UB-421 in Combination With Optimized Background Regimen in Patients With Multi-drug Resistant HIV-1 Infection
Started: 12/1/2023
Evaluation of the Hypoallergenicity of an Extensively Hydrolyzed Formula
Started: 4/1/2016
Study on the Tolerance and Efficacy of a New Anti Regurgitation Formula
Started: 6/1/2013
Cow Milk Allergy: Evaluation of the Efficacy of a New Thickened Extensively Hydrolyzed Formula in Infants With Confirmed Cow Milk Allergy
Started: 11/1/2013
Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years
Started: 12/18/2014
Open-Label Study of Oral Treprostinil in Digital Ulcers
Started: 9/1/2009
Remodulin as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn
Started: 7/29/2015
Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine
Started: 5/1/2009
Addition of UT-15C SR to Pulmonary Arterial Hypertension Patients Currently Receiving Tyvaso®
Started: 10/1/2011
Safety and Efficacy of Perioperative Remodulin® in Orthotopic Liver Transplant Recipients
Started: 6/1/2008
An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE
Started: 9/15/2016
Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE
Started: 2/3/2017
Long-term Safety and Efficacy of Ralinepag in Pulmonary Arterial Hypertension
Started: 7/8/2015
Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer
Started: 6/1/2017
Safety and Efficacy of APD811 in Pulmonary Arterial Hypertension
Started: 12/1/2014
Safety of Transition From Selexipag to Remodulin® Then Oral Treprostinil in Symptomatic Adult PAH
Started: 5/1/2017
Safety and Tolerability of Inhaled Treprostinil in Adult PH Due to COPD
Started: 4/1/2017
A Dose Response Study of UT-15C SR in Patients With Exercise-Induced Pulmonary Hypertension
Started: 4/1/2010
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis
Started: 2/1/2016
A Study of MAb-3F8 Plus Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus 13-cis-Retinoic Acid (RA) Plus GM-CSF in Primary Refractory Neuroblastoma Patients
Started: 8/1/2009
A Proof-of-concept Trial to Evaluate the Safety and Efficacy of UB-421 Plus Chidamide in Changing HIV Reservoirs
Started: 12/2/2021
The HIV Functional Cure Potential of UB-421 in ART Stabilized HIV-1 Patients
Started: 12/12/2018
the Study to Evaluate the Safety of UB-421 in Combination With Antiretroviral Therapy (ART) and the Efficacy in Reduction of HIV Viral Load and Proviral DNA as Compared to ART Alone in ART-experienced Viremic HIV-1 Patients
Started: 4/1/2020
To Investigate the Safety and Efficacy of UB-421 Monotherapy in HIV Infected Adults
Started: 6/1/2015
Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD
Started: 10/29/2025
Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD
Started: 6/1/2026
Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso
Started: 9/17/2019
A Safety Study of IV Stem Cell-derived Extracellular Vesicles (UNEX-42) in Preterm Neonates at High Risk for BPD
Started: 10/9/2019
Safety Study of PLX-PAD Cells to Treat Pulmonary Arterial Hypertension (PAH)
Started: 4/1/2013
ch14.18 Pharmacokinetic Study in High-risk Neuroblastoma
Started: 8/1/2012
Pharmacokinetic Interaction of Oral Treprostinil and Ethanol in Healthy Volunteers
Started: 9/1/2014
Dose Escalation, MTD, Safety and PK Study of a Single Dose SC Injection of TransCon PEG Treprostinil in Healthy Male Volunteers
Started: 7/1/2014
Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis
Started: 12/1/2008
The Effect of Renal Impairment on the Pharmacokinetics of Oral Treprostinil
Started: 5/1/2010
Comparative Bioavailability of Treprostinil Diethanolamine Manufactured by Two Independent Facilities
Started: 7/1/2010
A Bioavailability Study Comparing Treprostinil Diethanolamine Oral Tablets and Oral Solution in Healthy Volunteers
Started: 8/1/2010
Pharmacokinetic Linearity and Comparative Bioavailability of Treprostinil Diethanolamine
Started: 7/1/2010
Effect of Food on the Pharmacokinetics of Oral Treprostinil
Started: 9/1/2009
Effect of Esomeprazole on the Pharmacokinetics of Oral Treprostinil
Started: 9/1/2009
Study for Evaluation of the Safety, Pharmacokinetics, and Antiviral Activity of UB-421 Subcutaneous Formulation Administered in HIV-1 Infected Treatment Naive Patients
Started: 1/1/2021
Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UB-221 as an Add-on Therapy in CSU Patients
Started: 4/9/2019
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of UB-621 in Healthy Volunteers
Started: 12/1/2015
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of UB-921 in Healthy Volunteers
Started: 3/5/2018
A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension
Started: 10/20/2022
Rapid Switch From Flolan to Remodulin in the Outpatient Clinic
Started: 3/1/2008
EXPEDITE: A Study of Remodulin Induction Followed by Orenitram Optimization to Treat Pulmonary Arterial Hypertension
Started: 1/31/2019
Safety and Tolerability of Rapid Dose Titration of Subcutaneous Remodulin® Therapy in PAH Subjects (RAPID)
Started: 4/1/2012
Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension
Started: 2/1/2017
An Open Label Extension Study to Evaluate the Safety of Continued Therapy of Subcutanous Remodulin® in Pulmonary Arterial Hypertension
Started: 6/1/2017
Safety Evaluation of Inhaled Treprostinil Administration Following Transition From Inhaled Ventavis in Pulmonary Arterial Hypertension (PAH) Subjects
Started: 9/1/2008