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Hypertriglyceridemia

0 original drugs
0
Novel Drugs
7
Reformulations
0
Active Trials
6
Drug Targets

Hypertriglyceridemia has 0 FDA-approved novel treatments across 6 drug targets. Explore market leaders, treatments by mechanism, the clinical pipeline, and drug targets below.

Phase 3 Readouts Pro

5 active Phase 3 trials with confidence-graded completion dates.

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Q1 2027
Olezarsen
Ionis Pharmaceuticals, Inc.
Estimated · aging NCT05681351
Q4 2027
SHR-1918/ SHR-1918 placebo
Beijing Suncadia Pharmaceuticals Co., Ltd
Estimated · fresh NCT07349615
Q3 2028
Plozasiran Injection
Arrowhead Pharmaceuticals
Estimated · fresh NCT06822790
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Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Hypertriglyceridemia Treatments by Mechanism

Top 2 mechanisms across 2 industry trials with a known mechanism of action.

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Peroxisome Proliferator Receptor alpha Agonist
1 trials 1 sponsor
HMG-CoA Reductase Inhibitor
1 trials 1 sponsor

MoA derived from FDA pharmClassEpc when intervention matches an approved drug. Codenamed clinical-stage assets without an approved counterpart show "—" and aren't grouped here — they're still in the phase tables below.

Hypertriglyceridemia Clinical Pipeline by Phase

94 industry-sponsored trials across 44 sponsors

Precision Medicine Biomarkers

All biomarkers →

Biomarkers used for patient selection in Hypertriglyceridemia

Novel Hypertriglyceridemia Drugs by Company (New molecular entities)

No novel drugs found for this indication.

Reformulations (7 drugs) Click to expand

Reformulations are FDA-approved versions of existing molecules in new dosage forms (e.g., oral solution vs tablet, extended-release vs immediate-release). They require a new NDA but use an already-proven active ingredient.

Hypertriglyceridemia Drug Targets

Molecular targets of approved and investigational Hypertriglyceridemia drugs — 6 targets tracked.

Generic Drugs (9 ANDA approved) Click to expand

Drug Categories:

  • Novel Drugs: NDA Type 1/2 (new molecular entity) or original BLA
  • Reformulations: NDA Type 3/5 (new dosage form of existing molecule)
  • Biosimilars: BLA-approved biologics highly similar to reference products
  • Generics: ANDA-approved copies of small molecule drugs

View data sources and methodology