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Inflammation

1 original drugs
1
Novel Drugs
11
Reformulations
0
Active Trials
7
Drug Targets

Inflammation has 1 FDA-approved novel treatment, led by HARROW EYE across 7 drug targets. Explore market leaders, treatments by mechanism, the clinical pipeline, and drug targets below.

Inflammation Market Leaders

Companies with the most FDA-approved novel Inflammation drugs.

Phase 3 Readouts Pro

3 active Phase 3 trials with confidence-graded completion dates.

Full calendar →
Q4 2026
Ziltivekimab
Novo Nordisk
Estimated · fresh NCT06200207
Q4 2026
KSI-101
Kodiak Sciences Inc
Estimated · aging NCT06996080
Q1 2026
Maolactin
RDC Clinical Pty Ltd
Completed · awaiting NCT06444763

Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Inflammation Treatments by Mechanism

Top 4 mechanisms across 8 industry trials with a known mechanism of action.

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Corticosteroid
4 trials 2 sponsors
Glucocorticoid receptor
2 trials 1 sponsor
Phospholipase A2
1 trials 1 sponsor
Beta-2 adrenergic receptor/Glucocorticoid receptor
1 trials 1 sponsor

MoA derived from FDA pharmClassEpc when intervention matches an approved drug. Codenamed clinical-stage assets without an approved counterpart show "—" and aren't grouped here — they're still in the phase tables below.

Inflammation Clinical Pipeline by Phase

127 industry-sponsored trials across 70 sponsors

Novel Inflammation Drugs by Company (New molecular entities)

1 company has an FDA-approved novel drug for Inflammation.

Reformulations (11 drugs) Click to expand

Inflammation Drug Targets

Molecular targets of approved and investigational Inflammation drugs — 7 targets tracked.

Generic Drugs (8 ANDA approved) Click to expand

Drug Categories:

  • Novel Drugs: NDA Type 1/2 (new molecular entity) or original BLA
  • Reformulations: NDA Type 3/5 (new dosage form of existing molecule)
  • Biosimilars: BLA-approved biologics highly similar to reference products
  • Generics: ANDA-approved copies of small molecule drugs

View data sources and methodology