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Data updated: Jun 28, 2026

CRINETICS

Pharma
Oncology Execution: Needs Improvement

CRINETICS is a pharmaceutical company focused on Oncology. Key products include PALSONIFY.

2025
Since
1
Drugs
-
Trials
1
New Drugs (2yr)
Modality:
1 Small Molecules

FDA Novel Drug Designations

(2025)
1 Novel 1 Orphan
See 1 novel approval →
2025 PALSONIFY (PALTUSOTINE HYDROCHLORIDE) Orphan

CRINETICS at a Glance

  • Growing R&D activity with 6 trials in last 2 years
  • Fast trial execution (16 months median completion)

CRINETICS's Key Drugs

CRINETICS's core commercial portfolio centers on PALSONIFY, spanning Oncology — its most strategically important drugs approved in the last 15 years.

CRINETICS's Recent FDA Approvals

CRINETICS secured 1 new FDA approval for novel drugs (NDA/BLA) in the last two years.

CRINETICS's Therapeutic Areas

CRINETICS's approved drugs and pipeline span 1 therapeutic area, led by Oncology, across 0 biologic and 1 small-molecule drug. Weighted by commercial stage — approved drugs count most, then late-stage trials.

Oncology 100%
0 drugs Phase 3: 1 Phase 2: 1 Phase 1: 1

CRINETICS's Top Competitors

CRINETICS's closest competitors by therapeutic-area and drug-target overlap include Pfizer, Novartis, and Merck. Ranked by overlap in therapeutic areas and drug targets across approved drugs and pipeline.

CRINETICS Pipeline Snapshot

CRINETICS has 3 active clinical programs from ClinicalTrials.gov — 1 Phase 3, 1 Phase 2 and 1 Phase 1.

1
Phase 3
1
Phase 2
1
Phase 1

Phase 3 Readout Calendar Pro

3 Phase 3 trials with confidence-graded primary completion dates.

Full calendar →
Q2 2027
Atumelnant
Congenital Adrenal Hyperplasia
Estimated · fresh NCT07144163
Q3 2027
Paltusotine
Carcinoid Syndrome
Estimated · fresh NCT07087054
Q1 2030
Atumelnant
Congenital Adrenal Hyperplasia
Estimated · fresh NCT07159841

Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Pro Intelligence Preview

Deep insights for investors and analysts

Revenue Insights

  • PALSONIFY leads revenue
  • Drug-level revenue analysis

Trial Catalysts

  • Oncology pipeline focus
  • 3 Phase 3 readouts tracked
View readout calendar →

Patent Risk

  • Patent expiration timeline
  • Revenue at risk analysis

Compare Companies

  • Side-by-side pipeline analysis
  • Revenue & market share comparison

Execution Intelligence

  • Phase 3: 0/4 completed
  • Speed: 16 months avg
Unlock Full Intelligence

Revenue forecasts • Trial milestones • Patent risk modeling

How We Calculate These Metrics

Execution Quality Score

Measures trial completion rates weighted by phase importance. Phase 3 trials count 4x more than Phase 1 because late-stage completion is harder and more valuable.

What counts as "completed": A trial that reached its planned endpoint and reported results. Trials that were terminated early, withdrawn, or suspended are not counted as completed—these often indicate safety issues, lack of efficacy, or strategic pivots.

  • Excellent (80%+): Top-tier execution, most trials reach planned endpoints
  • Good (60-79%): Strong execution with occasional early terminations
  • Fair (40-59%): Average execution, notable rate of terminated/withdrawn trials
  • Needs Improvement (under 40%): High termination rates, execution challenges