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Data updated: Jun 28, 2026

KARYOPHARM THERAPS

Pharma
Oncology Execution: Needs Improvement

KARYOPHARM THERAPS is a pharmaceutical company focused on Oncology. Key products include XPOVIO.

2019
Since
1
Drugs
-
Trials
0
New Drugs (2yr)
Modality:
1 Small Molecules

FDA Novel Drug Designations

(2019)
1 Novel 1 First-in-Class 1 Orphan 1 Accelerated 1 Priority Review 1 Fast Track
See 1 novel approval →
2019 XPOVIO (SELINEXOR) First-in-Class · Orphan · Priority Review · Accelerated · Fast Track

KARYOPHARM THERAPS's Key Drugs

KARYOPHARM THERAPS's core commercial portfolio centers on XPOVIO, spanning Oncology — its most strategically important drugs approved in the last 15 years.

KARYOPHARM THERAPS's Recent FDA Approvals

New NDA/BLA approvals for KARYOPHARM THERAPS over the last two years — novel drugs only, excluding generics and label supplements.

No recent approvals

KARYOPHARM THERAPS's Therapeutic Areas

KARYOPHARM THERAPS's approved drugs and pipeline span 1 therapeutic area, led by Oncology, across 0 biologic and 1 small-molecule drug. Weighted by commercial stage — approved drugs count most, then late-stage trials.

Oncology 100%
1 drugs

KARYOPHARM THERAPS's Top Competitors

KARYOPHARM THERAPS's closest competitors by therapeutic-area and drug-target overlap include Pfizer, Novartis, and Merck. Ranked by overlap in therapeutic areas and drug targets across approved drugs and pipeline.

KARYOPHARM THERAPS Pipeline Snapshot

Active clinical trials for KARYOPHARM THERAPS across all therapeutic areas, from ClinicalTrials.gov.

No active pipeline data available

Pro Intelligence Preview

Deep insights for investors and analysts

Revenue Insights

  • XPOVIO leads revenue
  • Drug-level revenue analysis

Trial Catalysts

  • Oncology pipeline focus
  • Phase 3 readout tracking

Patent Risk

  • Patent expiration timeline
  • Revenue at risk analysis

Compare Companies

  • Side-by-side pipeline analysis
  • Revenue & market share comparison

Execution Intelligence

  • Phase 3: 2/4 completed
  • Speed: 39 months avg
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Revenue forecasts • Trial milestones • Patent risk modeling

How We Calculate These Metrics

Execution Quality Score

Measures trial completion rates weighted by phase importance. Phase 3 trials count 4x more than Phase 1 because late-stage completion is harder and more valuable.

What counts as "completed": A trial that reached its planned endpoint and reported results. Trials that were terminated early, withdrawn, or suspended are not counted as completed—these often indicate safety issues, lack of efficacy, or strategic pivots.

  • Excellent (80%+): Top-tier execution, most trials reach planned endpoints
  • Good (60-79%): Strong execution with occasional early terminations
  • Fair (40-59%): Average execution, notable rate of terminated/withdrawn trials
  • Needs Improvement (under 40%): High termination rates, execution challenges