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Data updated: Jun 28, 2026

DIANEAL PD-2 W/ DEXTROSE 1.5% IN PLASTIC CONTAINER (calcium chloride) · VANTIVE US HLTHCARE

Renal Approved 1978-09-27

Ringer’s Injection provides a source of water and essential electrolytes for both adult and pediatric patients. It helps patients who require fluid replacement or the restoration of key minerals in the body. This solution is used to support proper hydration and maintain the balance of electrolytes necessary for various bodily functions.

How DIANEAL PD-2 W/ DEXTROSE 1.5% IN PLASTIC CONTAINER Works

This injection works by supplying the body with critical ions that manage fluid distribution and osmotic pressure. Sodium and chloride help regulate the acid-base equilibrium, while potassium and calcium support vital processes like nerve signaling, muscle contraction, and blood clotting.

2
Indications
--
Phase 3 Trials
47
Years on Market

Details

Status
Prescription
First Approved
1978-09-27
Routes
INTRAPERITONEAL
Dosage Forms
SOLUTION

DIANEAL PD-2 W/ DEXTROSE 1.5% IN PLASTIC CONTAINER Approval History

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Original
New Indication
New Form
Label Update
120 FDA actions from 1978 to 2023
Jun 2023 SUPPL
Label · Labeling
Dec 2016 SUPPL
Mfg · Manufacturing (CMC)
Aug 2016 SUPPL
Label · Labeling

What DIANEAL PD-2 W/ DEXTROSE 1.5% IN PLASTIC CONTAINER Treats

2 indications

DIANEAL PD-2 W/ DEXTROSE 1.5% IN PLASTIC CONTAINER is approved for 2 conditions since its original approval in 1978. These indications span multiple therapeutic areas including oncology, immunology, and more.

Source: FDA Label

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Clinical Trial Registry

7 trials
Trial Sponsor ID Phase Status Title
NCT07550413 20042026 Ph 2 not yet recruiting Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section
NCT03772990 ICARUS 21/2019 Ph 4 completed Calcium Administration in Cardiac Surgery
NCT05027048 CALBLOC results posted 62206 MRTG-02-15-2022-Ansari, YIG-2020 Ph 3 completed Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery
NCT04153435 COCA results posted 00002 2019-003387-46 Ph 2 completed Calcium for Out-of-Hospital Cardiac Arrest
NCT03867383 results posted 43076 Ph 1, Ph 2 completed Calcium Chloride for Prevention of Uterine Atony During Cesarean
NCT01941914 AA1310 Ph 1 completed Calcium Electroporation for the Treatment of Keloids
NCT00955266 results posted 2009-P-000052 Ph 4 terminated A Trial of Intravenous Calcium and Myocardial Diastolic Dysfunction During Separation From Cardiopulmonary Bypass
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

DIANEAL PD-2 W/ DEXTROSE 1.5% IN PLASTIC CONTAINER FDA Label Details

Indications & Usage

FDA Label (PDF)

Ringer’s Injection is indicated for use as a source of water and electrolytes in adults and pediatric patients. Ringer’s Injection is indicated for use as a source of water and electrolytes in adults and pediatric patients.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.