DOXAZOSIN MESYLATE · ACCORD HLTHCARE
Doxazosin mesylate treats high blood pressure and helps patients manage the symptoms of benign prostatic hyperplasia (BPH). By lowering blood pressure, it helps reduce the risk of serious cardiovascular events like strokes and heart attacks. For men with BPH, this medication addresses issues such as frequent nighttime urination, weak urine flow, and incomplete bladder emptying.
How DOXAZOSIN MESYLATE Works
This medication works by selectively blocking alpha 1 adrenergic receptors, which are found in high concentrations in the prostate and blood vessels. In the prostate and bladder neck, this blockade relaxes smooth muscle tone to reduce urethral resistance and improve urine flow. For blood pressure management, the drug decreases systemic vascular resistance to help lower overall pressure.
Details
- Status
- Prescription
- First Approved
- 1990-11-02
- Routes
- ORAL
- Dosage Forms
- TABLET
Companies
DOXAZOSIN MESYLATE Approval History
What DOXAZOSIN MESYLATE Treats
2 indicationsDOXAZOSIN MESYLATE is approved for 2 conditions since its original approval in 2000. These indications span multiple therapeutic areas including oncology, immunology, and more.
DOXAZOSIN MESYLATE Competitive Set
ProThree rings of competition based on shared molecular targets and treated indications.
Indication competitors
Same indication, different mechanism — what else might this patient receive?
Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.
What's emerging in DOXAZOSIN MESYLATE's indications
See all emerging drugs →Phase 3 candidates targeting molecules with no FDA-approved drug, in indications DOXAZOSIN MESYLATE treats. First-in-class if their pivotal trials read out positive.
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3 of 20FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.
Active Pipeline
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Key Completed Trials
Completed studies with published results, ranked by significance
Trial Timeline
Full development history with FDA approval milestones
Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
DOXAZOSIN MESYLATE FDA Label Details
Indications & Usage
FDA Label (PDF)Doxazosin tablets are an alpha 1 adrenergic antagonist indicated for: Signs and symptoms of Benign Prostatic Hyperplasia (BPH) Treatment of Hypertension 1.1 Benign Prostatic Hyperplasia (BPH) Doxazosin tablets are indicated for the treatment of the signs and symptoms of BPH. 1.2 Hypertension Doxazosin tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk offatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a ...
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Full clinical data, patents, trials, and competitive landscape for doxazosin mesylate.
Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.