TheraRadar
Data updated: Jun 28, 2026

NEXIUM 24HR (esomeprazole magnesium) · AstraZeneca

Infectious Disease Approved 2014-03-28

NEXIUM 24HR is FDA-approved to treat 8 conditions (same as ESOMEPRAZOLE MAGNESIUM).

2
Indications
--
Phase 3 Trials
12
Years on Market

Details

Status
Over-the-counter
First Approved
2014-03-28
Routes
ORAL
Dosage Forms
CAPSULE, DELAYED RELEASE, TABLET, DELAYED RELEASE

Companies

Active Ingredient: ESOMEPRAZOLE MAGNESIUM

NEXIUM 24HR Approval History

2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
16 FDA actions from 2014 to 2022
Sep 2022 SUPPL
Label · Labeling
Dec 2020 SUPPL
Label · Labeling
Apr 2019 SUPPL
Label · Labeling

What NEXIUM 24HR Treats

8 indications

NEXIUM 24HR is approved for 8 conditions since its original approval in 2014. These indications span multiple therapeutic areas including oncology, immunology, and more.

Same approved indications as ESOMEPRAZOLE MAGNESIUM (same active ingredient).

Source: FDA Label
📋

Clinical Trial Registry

1 trials
Trial Sponsor ID Phase Status Title
NCT01135472 08197 Ph 1 completed Plasm Gastrin Concentrations in Response to Nexium Administration in Healthy Volunteers
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

Pro

Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

NEXIUM 24HR FDA Label Details

Indications & Usage

FDA Label (PDF)

NEXIUM 24HR is FDA-approved to treat 8 conditions — same approved indications as ESOMEPRAZOLE MAGNESIUM.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.