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Data updated: Jun 28, 2026

PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER (calcium chloride) · VANTIVE US HLTHCARE

Other Approved 2015-01-13

This solution serves as a source of water and electrolytes for both adult and pediatric patients. It helps patients maintain proper hydration and provides essential minerals required for various bodily functions. It is used to support fluid balance and ensure the body has the necessary components for nerve and muscle activity.

How PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER Works

It works by replenishing sodium to control water distribution and potassium to support nerve conduction and heart contractions. Additionally, it provides calcium for blood clotting and cardiac function, along with chloride to help regulate the body's acid-base balance.

1
Indication
--
Phase 3 Trials
11
Years on Market

Details

Status
Prescription
First Approved
2015-01-13
Routes
INJECTION
Dosage Forms
INJECTABLE

PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER Approval History

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
6 FDA actions from 2015 to 2023
May 2023 SUPPL
Label · Labeling
Nov 2018 SUPPL
Label · Labeling
Jun 2017 SUPPL
Label · Labeling

What PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER Treats

2 indications

PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER is approved for 2 conditions since its original approval in 2015. These indications span multiple therapeutic areas including oncology, immunology, and more.

Source: FDA Label

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Clinical Trial Registry

7 trials
Trial Sponsor ID Phase Status Title
NCT07550413 20042026 Ph 2 not yet recruiting Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section
NCT03772990 ICARUS 21/2019 Ph 4 completed Calcium Administration in Cardiac Surgery
NCT05027048 CALBLOC results posted 62206 MRTG-02-15-2022-Ansari, YIG-2020 Ph 3 completed Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery
NCT04153435 COCA results posted 00002 2019-003387-46 Ph 2 completed Calcium for Out-of-Hospital Cardiac Arrest
NCT03867383 results posted 43076 Ph 1, Ph 2 completed Calcium Chloride for Prevention of Uterine Atony During Cesarean
NCT01941914 AA1310 Ph 1 completed Calcium Electroporation for the Treatment of Keloids
NCT00955266 results posted 2009-P-000052 Ph 4 terminated A Trial of Intravenous Calcium and Myocardial Diastolic Dysfunction During Separation From Cardiopulmonary Bypass
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER FDA Label Details

Indications & Usage

FDA Label (PDF)

Ringer’s Injection is indicated for use as a source of water and electrolytes in adults and pediatric patients. Ringer’s Injection is indicated for use as a source of water and electrolytes in adults and pediatric patients.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.