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Data updated: Jun 28, 2026

POTASSIUM CHLORIDE 10MEQ IN DEXTROSE 5% AND LACTATED RINGER'S IN PLASTIC CONTAINER (calcium chloride) · OTSUKA ICU MEDCL

Other Approved 1985-04-05

This intravenous solution helps patients who require supplemental water and electrolytes, including both adults and children. It is used to maintain proper hydration and ensure the body has the necessary minerals for basic physiological functions. Healthcare providers use this to support fluid balance and provide essential nutrients like potassium and calcium.

How POTASSIUM CHLORIDE 10MEQ IN DEXTROSE 5% AND LACTATED RINGER'S IN PLASTIC CONTAINER Works

This solution works by replenishing the body's supply of essential ions and water. Sodium helps regulate fluid distribution and acid-base balance, while potassium supports nerve signaling and heart muscle contraction. Additionally, the included calcium aids in blood clotting and normal cardiac function.

2
Indications
--
Phase 3 Trials
41
Years on Market

Details

Status
Discontinued
First Approved
1985-04-05
Routes
INJECTION
Dosage Forms
INJECTABLE

POTASSIUM CHLORIDE 10MEQ IN DEXTROSE 5% AND LACTATED RINGER'S IN PLASTIC CONTAINER Approval History

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Original
New Indication
New Form
Label Update
72 FDA actions from 1985 to 2025
Nov 2025 SUPPL
Label · Labeling
Oct 2019 SUPPL
Label · Labeling
Dec 2017 SUPPL
Label · Labeling

What POTASSIUM CHLORIDE 10MEQ IN DEXTROSE 5% AND LACTATED RINGER'S IN PLASTIC CONTAINER Treats

2 indications

POTASSIUM CHLORIDE 10MEQ IN DEXTROSE 5% AND LACTATED RINGER'S IN PLASTIC CONTAINER is approved for 2 conditions since its original approval in 1985. These indications span multiple therapeutic areas including oncology, immunology, and more.

Source: FDA Label

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Clinical Trial Registry

7 trials
Trial Sponsor ID Phase Status Title
NCT07550413 20042026 Ph 2 not yet recruiting Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section
NCT03772990 ICARUS 21/2019 Ph 4 completed Calcium Administration in Cardiac Surgery
NCT05027048 CALBLOC results posted 62206 MRTG-02-15-2022-Ansari, YIG-2020 Ph 3 completed Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery
NCT04153435 COCA results posted 00002 2019-003387-46 Ph 2 completed Calcium for Out-of-Hospital Cardiac Arrest
NCT03867383 results posted 43076 Ph 1, Ph 2 completed Calcium Chloride for Prevention of Uterine Atony During Cesarean
NCT01941914 AA1310 Ph 1 completed Calcium Electroporation for the Treatment of Keloids
NCT00955266 results posted 2009-P-000052 Ph 4 terminated A Trial of Intravenous Calcium and Myocardial Diastolic Dysfunction During Separation From Cardiopulmonary Bypass
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

POTASSIUM CHLORIDE 10MEQ IN DEXTROSE 5% AND LACTATED RINGER'S IN PLASTIC CONTAINER FDA Label Details

Indications & Usage

FDA Label (PDF)

Ringer’s Injection is indicated for use as a source of water and electrolytes in adults and pediatric patients. Ringer’s Injection is indicated for use as a source of water and electrolytes in adults and pediatric patients.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.