TheraRadar
Class patent landscape

Atypical Antipsychotic

Cross-drug patent estate across 14 approved drugs in the atypical antipsychotic class. Loss-of-exclusivity timeline, sponsor concentration, and per-drug links to full patent landscapes.

Approved drugs
14
with patent data
OB patents
103
across the class
Patent families
40
1,421 docs · 55 countries
Earliest US LOE
Mar 1, 2027
first drug off patent
Latest US LOE
Mar 16, 2042
last drug off patent

Loss-of-exclusivity waterfall

Drugs in the atypical antipsychotic class sorted by US Orange Book expiry — earliest LOE first. Each row links to the drug's full patent landscape.

Drug Sponsor OB patents Families Intl docs Latest US expiry
ABILIFY
aripiprazole
OTSUKA 2 2 68 Mar 1, 2027
+1y
View →
PERSERIS KIT
risperidone
INDIVIOR 10 2 75 Feb 12, 2028
+2y
View →
VERSACLOZ
clozapine
DOUGLAS PHARMS 1 1 13 Apr 30, 2028
+2y
View →
VRAYLAR
cariprazine hydrochloride
AbbVie 5 3 165 Sep 16, 2029
+3y
View →
FANAPT
iloperidone
VANDA PHARMS INC 8 7 112 Dec 27, 2031
+5y
View →
RYKINDO
risperidone
SHANDONG LUYE 5 1 57 Apr 9, 2032
+6y
View →
REXULTI
brexpiprazole
OTSUKA 11 2 131 Apr 11, 2033
+7y
View →
ABILIFY ASIMTUFII
aripiprazole
OTSUKA 4 1 105 Apr 22, 2033
+7y
View →
SECUADO
asenapine
HISAMITSU 6 3 65 Sep 21, 2033
+7y
View →
ABILIFY MAINTENA KIT
aripiprazole
OTSUKA PHARM CO LTD 6 2 72 Apr 5, 2034
+8y
View →
CAPLYTA
lumateperone tosylate
INTRA-CELLULAR 23 8 310 Dec 9, 2040
+14y
View →
LYBALVI
olanzapine
ALKERMES INC 14 3 111 Nov 11, 2041
+15y
View →
OPIPZA
aripiprazole
XIAMEN LP PHARM CO 2 1 6 Dec 14, 2041
+15y
View →
UZEDY
risperidone
Teva 6 4 131 Mar 16, 2042
+16y
View →

Sponsor concentration

Which companies anchor the IP across this class.

Pro Sponsor concentration — Which sponsors anchor the IP across the class
See what Pro includes ↓

Methodology & data sources

  • Drugs in class: aggregated from drug.pharmClassEpc field. Drugs without EPC tags are not included here (data gap, not coverage limitation).
  • Patent data: per-drug patent thickets from FDA Orange Book / Purple Book + BigQuery family expansion. See individual drug patent pages for source detail.
  • LOE waterfall: sorted by latestPatentExpiry from Orange Book. Reflects US patent term adjustments (PTA) but not exclusivity overlays (ODE, NPP, PED).
  • Class-level analysis: sums across per-drug thickets. Same patent family may appear in multiple drugs (e.g., Jakafi + Opzelura share composition family) — counted once per family per drug for OB totals.
Intelligence, not legal advice. Class-level summary reflects what's listed publicly. Generic launch dynamics depend on per-drug NCE/ODE/PED overlays, ANDA Para IV outcomes, and BPCIA settlements not captured here.

TheraRadar Pro — patent intelligence

Free covers what's publicly listed: Orange Book patents, basic stats, composition expiry. Pro adds the deeper view: LLM-driven estate analysis, full international family thicket, and (coming soon) alerts + exports.

Always free

  • Orange Book patent table (every patent, family, use code, expiry)
  • Stat strip — OB count, families, global doc footprint, multiplier
  • Composition family priority + nominal global expiry
  • International vs US expiry comparison
  • Coverage status + methodology
  • LOE waterfall across all approved drugs in the class
PRO

What Pro adds today

  • Estate analysis (sections 2-5) — Composition anchor, lifecycle layers, international vs US, strategic outlook
  • Full patent families table — Country lists, doc counts, priority dates per family
  • Sponsor concentration — Who owns the IP across the class
  • International nominal expiries — Priority + 20 years per family with global vs US gap
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Class patent data updated: Jun 17, 2026